VH3.15 repertoire analysis of the splenic B cell subsets of an 8-mo-old child
| Donor | B cell subset | Transcripts | Number of peaks analyzeda | Total number of sequences | Number of different VDJ junctions | Clonal diversityb | P valuec |
|---|---|---|---|---|---|---|---|
| % | |||||||
| D3 | IgD+CD27+ | VH3.15 μ | 3 | 58 | 56 | 97 | |
| Naives | VH3.15 μ | 3 | 71 | 64 | 90 | ||
| IgD−CD27+ (switched + GC) | VH3.15 γ | 3 | 73 | 35 | 48 | 3 × 10−9 | |
| CD38+CD24− (GC) | VH3.15 μ | 6 | 133 | 71 | 53 | 4 × 10−9 | |
| VH3.15 γ | 5 | 98 | 51 | 52 | 10−8 |
| Donor | B cell subset | Transcripts | Number of peaks analyzed | Total number of sequences | Number of different VDJ junctions | Clonal diversity | P value |
|---|---|---|---|---|---|---|---|
| D3 | IgD+CD27+ | VH3.15 μ | 3 | 58 | 56 | 97 | |
| Naives | VH3.15 μ | 3 | 71 | 64 | 90 | ||
| IgD−CD27+ (switched + GC) | VH3.15 γ | 3 | 73 | 35 | 48 | 3 × 10−9 | |
| CD38+CD24− (GC) | VH3.15 μ | 6 | 133 | 71 | 53 | 4 × 10−9 | |
| VH3.15 γ | 5 | 98 | 51 | 52 | 10−8 |
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