Number of IFN-γ+ CD3+CD4+ or IFN-γ+ CD3+CD8+ cells in the lungs of sensitized and challenged CD8−/− mice that received DMSO-TEFF or GSI-TEFF cells
. | CD4+IFN-γ+ (×104) . | CD8+IFN-γ+ (×104) . |
|---|---|---|
| CD8-deficient | 18.0 ± 1.2 | — |
| DMSO-TEFF | 35.0 ± 5.6 | 21.6 ± 4.2 |
| GSI-TEFF | 50.7 ± 3.8a | 14.3 ± 1.3b |
. | CD4+IFN-γ+ (×104) . | CD8+IFN-γ+ (×104) . |
|---|---|---|
| CD8-deficient | 18.0 ± 1.2 | — |
| DMSO-TEFF | 35.0 ± 5.6 | 21.6 ± 4.2 |
| GSI-TEFF | 50.7 ± 3.8a | 14.3 ± 1.3b |
Mean values ± SEM are given. CD8-deficient, OVA-sensitized and challenged CD8-deficient mice; DMSO-TEFF, DMSO-treated TEFF cell recipient CD8-deficient mice that were OVA sensitized and challenged; GSI-TEFF, GSI-treated TEFF cell recipient CD8-deficient mice that were OVA sensitized and challenged.
P < 0.05 compared between GSI-TEFF cells versus CD8-deficient and DMSO-TEFF cells.
P < 0.05 compared between GSI-TEFF cells versus DMSO-TEFF cells.