Table I. Arthritis development following... | Rockefeller University Press

Table I.

Arthritis development following Tnf^ΔARE BM reconstitution of lethally irradiated recipients

Donor genotype	Recipient genotype	Arthritis development
WT	WT	0/20
Tnf^ΔARE/+	WT	19/21
Tnf^{ΔARE/ΔARE TnfRI−/−}	WT	25/25
Tnf^ΔARE/+	TnfRI^−/−	0/8

BM isolated from 2-mo-old female B6,129 mice (donor genotype) was engrafted into 6–8-wk-old syngeneic, lethally irradiated, female mice (recipient genotype). Assessment of arthritis development was based on histopathological evaluation of joint samples at 12 wk after transfer.

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Donor genotype	Recipient genotype	Arthritis development
WT	WT	0/20
Tnf^ΔARE/+	WT	19/21
Tnf^{ΔARE/ΔARE TnfRI−/−}	WT	25/25
Tnf^ΔARE/+	TnfRI^−/−	0/8

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