Table I.

Plasma total cholesterol in BMGFP+LDLr−/− and LDLr−/−TLR2−/− chimeric mice

Weeks of HFD consumptiona
0
2
4
6
8
10
HFD-ave.b
LDLr−/− 241 ± 18 768 ± 75 1,064 ± 54 982 ± 91 1,064 ± 29 983 ± 97 972 ± 38 
 n = 3 n = 4 n = 4 n = 4 n = 4 n = 4 n = 20 
LDLr−/−TLR2−/− 230 ± 8 784 ± 122 829 ± 45 936 ± 25 891 ± 69 1,013 ± 126 887 ± 37 
 n = 3 n = 3 n = 4 n = 3 n = 4 n = 3 n = 17 
Weeks of HFD consumptiona
0
2
4
6
8
10
HFD-ave.b
LDLr−/− 241 ± 18 768 ± 75 1,064 ± 54 982 ± 91 1,064 ± 29 983 ± 97 972 ± 38 
 n = 3 n = 4 n = 4 n = 4 n = 4 n = 4 n = 20 
LDLr−/−TLR2−/− 230 ± 8 784 ± 122 829 ± 45 936 ± 25 891 ± 69 1,013 ± 126 887 ± 37 
 n = 3 n = 3 n = 4 n = 3 n = 4 n = 3 n = 17 
a

All values are reported as milligrams per deciliter ± the SEM. n, number of mice used for each time point

b

HFD-ave. was calculated from the cholesterol measurements taken during the HFD feeding period (2–10-wk time points).

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