Members of MCC and associated cytosolic proteins
| Name . | ORF . | Molecular function . | Biological process . | TMDs . | Localization references . |
|---|---|---|---|---|---|
| Integral MCC components | |||||
| Can1 | YEL063C | H+-driven arginine permease | Basic amino acid transport | 12 | Malínská et al., 2003 |
| Fur4 | YBR021W | H+-driven uracil permease | Uracil transport | 12 | Malínská et al., 2004 |
| Tat2 | YOL020W | H+-driven tryptophan and tyrosine permease | Aromatic amino acid transport | 12 | Grossmann et al., 2007 |
| Nce102 | YPR149W | Unknown | Nonclassical protein secretion | 4 | This study |
| Fmp45 | YDL222C | Unknown | Ascospore formation | 4 | Young et al., 2002 |
| Sur7 | YML052W | Unknown | Ascospore formation | 4 | Malínská et al., 2003; Young et al., 2002 |
| Ygr131w | YGR131W | Unknown | Unknown | 4 | This study |
| Ylr414c | YLR414C | Unknown | Unknown | 4 | This study |
| Ynl194c | YNL194C | Unknown | Ascospore formation | 4 | Young et al., 2002 |
| MCC-associated cytosolic proteins | |||||
| Lsp1 | YPL004C | Protein kinase inhibitor activity | Endocytosis (eisosome) | 0 | Walther et al., 2006 |
| Mdg1 | YNL173C | Unknown | Pheromone signaling | 0 | This study |
| Pil1 | YGR086C | Protein kinase inhibitor activity | Endocytosis (eisosome) | 0 | Walther et al., 2006 |
| Pkh1 | YDR490C | Ser/Thr protein kinase | Endocytosis | 0 | Roelants et al., 2002; Walther et al., 2007; Luo et al., 2008 |
| Pkh2 | YOL100W | Ser/Thr protein kinase | Endocytosis | 0 | Roelants et al., 2002; Walther et al., 2007; Luo et al., 2008 |
| Pst2 | YDR032C | Unknown | Unknown | 0 | This study |
| Rfs1 | YBR052C | Unknown | Unknown | 0 | This study |
| Slm1 | YIL105C | Phosphoinositide binding | Actin cytoskeleton organization | 0 | This study; Fadri et al., 2005 |
| Slm2 | YNL047C | Phosphoinositide binding | Actin cytoskeleton organization | 0 | Fadri et al., 2005 |
| Ycp4 | YCR004C | Unknown | Unknown | 0 | This study |
| Ygr130c | YGR130C | Unknown | Unknown | 0 | This study |
| Ymr031c | YMR031C | Unknown | Unknown | 0 | This study |
| Name . | ORF . | Molecular function . | Biological process . | TMDs . | Localization references . |
|---|---|---|---|---|---|
| Integral MCC components | |||||
| Can1 | YEL063C | H+-driven arginine permease | Basic amino acid transport | 12 | Malínská et al., 2003 |
| Fur4 | YBR021W | H+-driven uracil permease | Uracil transport | 12 | Malínská et al., 2004 |
| Tat2 | YOL020W | H+-driven tryptophan and tyrosine permease | Aromatic amino acid transport | 12 | Grossmann et al., 2007 |
| Nce102 | YPR149W | Unknown | Nonclassical protein secretion | 4 | This study |
| Fmp45 | YDL222C | Unknown | Ascospore formation | 4 | Young et al., 2002 |
| Sur7 | YML052W | Unknown | Ascospore formation | 4 | Malínská et al., 2003; Young et al., 2002 |
| Ygr131w | YGR131W | Unknown | Unknown | 4 | This study |
| Ylr414c | YLR414C | Unknown | Unknown | 4 | This study |
| Ynl194c | YNL194C | Unknown | Ascospore formation | 4 | Young et al., 2002 |
| MCC-associated cytosolic proteins | |||||
| Lsp1 | YPL004C | Protein kinase inhibitor activity | Endocytosis (eisosome) | 0 | Walther et al., 2006 |
| Mdg1 | YNL173C | Unknown | Pheromone signaling | 0 | This study |
| Pil1 | YGR086C | Protein kinase inhibitor activity | Endocytosis (eisosome) | 0 | Walther et al., 2006 |
| Pkh1 | YDR490C | Ser/Thr protein kinase | Endocytosis | 0 | Roelants et al., 2002; Walther et al., 2007; Luo et al., 2008 |
| Pkh2 | YOL100W | Ser/Thr protein kinase | Endocytosis | 0 | Roelants et al., 2002; Walther et al., 2007; Luo et al., 2008 |
| Pst2 | YDR032C | Unknown | Unknown | 0 | This study |
| Rfs1 | YBR052C | Unknown | Unknown | 0 | This study |
| Slm1 | YIL105C | Phosphoinositide binding | Actin cytoskeleton organization | 0 | This study; Fadri et al., 2005 |
| Slm2 | YNL047C | Phosphoinositide binding | Actin cytoskeleton organization | 0 | Fadri et al., 2005 |
| Ycp4 | YCR004C | Unknown | Unknown | 0 | This study |
| Ygr130c | YGR130C | Unknown | Unknown | 0 | This study |
| Ymr031c | YMR031C | Unknown | Unknown | 0 | This study |
TMD, transmembrane domain. Putative transmembrane domains are given as predicted by TmPred and transmembrane hidden Markov model (TMHMM).