Table I.

Characterization of integrin nanodiscs

Samplea MW MW after subtract empty nanodiscs Integrins per nanodiscs 
Empty nanondiscs 80,500 ± 582 D 0 0 
Integrin nanodiscs, specie 1 299,000 ± 1,483 D 218,500 1 
Integrin nanodiscs, specie 2 530,000 ± 5,451 D 449,500 2 
Sampleb Sedimentation coefficient (S*) Areas under S* peak Percentage of total 
Nanodiscs, 1 integrin specie 8.56E-13 2.86905 77.4 
Nanodiscs, 2 integrin specie 1.47E-12 0.83728 22.6 
Samplea MW MW after subtract empty nanodiscs Integrins per nanodiscs 
Empty nanondiscs 80,500 ± 582 D 0 0 
Integrin nanodiscs, specie 1 299,000 ± 1,483 D 218,500 1 
Integrin nanodiscs, specie 2 530,000 ± 5,451 D 449,500 2 
Sampleb Sedimentation coefficient (S*) Areas under S* peak Percentage of total 
Nanodiscs, 1 integrin specie 8.56E-13 2.86905 77.4 
Nanodiscs, 2 integrin specie 1.47E-12 0.83728 22.6 
a

Molecular weight measurement of empty nanodiscs, single-integrin nanodiscs and dual-integrin nanodiscs.

b

Sedimentation coefficient determination of single-integrin nanodiscs and dual-integrin nanodiscs, and their respective percentage in the total population.

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