Search results for selected nuclear protein ORFs in representatives of five eukaryotic supergroup lineages, listing genes or ORFs homologous to each queried polypeptide that were detected in completed genomes of representative supergroup lineages (Opisthokonts, Amoebozoa, Archaeplastida, Chromalveolates, and Excavates) in GenBank using reciprocal BLAST with e-values > 0.01. This method detected ORFs representing four of the seven known human LEM domain genes, and is therefore quite stringent. Multiple ORFs, for example LUMA-related ORFs in Paramecium, were not annotated so the number of encoding gene(s) remains to be determined.