Table I.

Model variables and parameters

Symbol Meaning Parameter values used References 
Fstallklp/ncd Stall force of the motor 1–10 pN Schnitzer et al., 2000; Valentine et al., 2006  
Fdetklp/ncd Detachment force of the motor 1–10 pN Valentine et al., 2006  
Vmaxklp/ncd Maximal velocity of the motor 0.01–0.5 μm/s Tao et al., 2006  
Vbackklp/ncd Backward velocity of the motor 0.001–5 μm/s Carter and Cross, 2005  
konklp/ncd Binding rate of motors 0.01–10 s−1 Krzysiak et al., 2008  
koff0,klp/ncd Load-free detachment rate of motors 0.01–10 s−1 Krzysiak et al., 2008  
k, n Number of bound motors per unit length AP MT up to 800 μm−1 Sharp et al., 1999a  
κ Spring constant of HL-KLP61F 10–200 pNs/μm Tawada and Sekimoto, 1991  
ζ(tSpring constant of nuclear lamin-B envelope 100–200 pNs/μm Dahl et al., 2004; Cytrynbaum et al., 2005  
μ Effective spindle pole viscous drag coefficient 200 pNs/μm Marshall et al., 2001  
vMT Instantaneous velocity of MT variable This study 
vpole Instantaneous velocity of spindle poles variable This study 
νg MT plus end growth rate 0.1–0.4 μm/s Cheerambathur et al., 2007  
νs MT plus end shrinkage rate 0.1–0.4 μm/s Cheerambathur et al., 2007  
fres MT plus end rescue frequency 0.01–0.5 s−1 Cheerambathur et al., 2007  
fcat MT plus end catastrophe frequency 0.01–0.5 s−1 Cheerambathur et al., 2007  
Symbol Meaning Parameter values used References 
Fstallklp/ncd Stall force of the motor 1–10 pN Schnitzer et al., 2000; Valentine et al., 2006  
Fdetklp/ncd Detachment force of the motor 1–10 pN Valentine et al., 2006  
Vmaxklp/ncd Maximal velocity of the motor 0.01–0.5 μm/s Tao et al., 2006  
Vbackklp/ncd Backward velocity of the motor 0.001–5 μm/s Carter and Cross, 2005  
konklp/ncd Binding rate of motors 0.01–10 s−1 Krzysiak et al., 2008  
koff0,klp/ncd Load-free detachment rate of motors 0.01–10 s−1 Krzysiak et al., 2008  
k, n Number of bound motors per unit length AP MT up to 800 μm−1 Sharp et al., 1999a  
κ Spring constant of HL-KLP61F 10–200 pNs/μm Tawada and Sekimoto, 1991  
ζ(tSpring constant of nuclear lamin-B envelope 100–200 pNs/μm Dahl et al., 2004; Cytrynbaum et al., 2005  
μ Effective spindle pole viscous drag coefficient 200 pNs/μm Marshall et al., 2001  
vMT Instantaneous velocity of MT variable This study 
vpole Instantaneous velocity of spindle poles variable This study 
νg MT plus end growth rate 0.1–0.4 μm/s Cheerambathur et al., 2007  
νs MT plus end shrinkage rate 0.1–0.4 μm/s Cheerambathur et al., 2007  
fres MT plus end rescue frequency 0.01–0.5 s−1 Cheerambathur et al., 2007  
fcat MT plus end catastrophe frequency 0.01–0.5 s−1 Cheerambathur et al., 2007  

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