Cargoes inhibited in secretion upon ADF and cofilin1 knockdown (class B)
| Protein name | Unique peptides | Ratio (H/L) control/RNAi |
| Secretogranin-2 | 2 | 11 |
| Collagen α1 (III) chain | 3 | 4.6 |
| Lumican | 3 | 3 |
| Collagen α1 (I) chain | 4 | 2.8 |
| Collagen α1(XVIII) chain | 4 | 2 |
| Agrin (secreted form) | 16 | 1.9 |
| Collagen α1(VII) chain | 42 | 1.9 |
| Collagen α1(XV) chain | 6 | 1.9 |
| Immunoglobulin superfamily member 10 | 7 | 1.8 |
| Perlecan | 51 | 1.6 |
| Protein name | Unique peptides | Ratio (H/L) control/RNAi |
| Secretogranin-2 | 2 | 11 |
| Collagen α1 (III) chain | 3 | 4.6 |
| Lumican | 3 | 3 |
| Collagen α1 (I) chain | 4 | 2.8 |
| Collagen α1(XVIII) chain | 4 | 2 |
| Agrin (secreted form) | 16 | 1.9 |
| Collagen α1(VII) chain | 42 | 1.9 |
| Collagen α1(XV) chain | 6 | 1.9 |
| Immunoglobulin superfamily member 10 | 7 | 1.8 |
| Perlecan | 51 | 1.6 |
Secretion of proteins into cell culture media from control and ADF and cofilin1 siRNA–treated HeLa cells was analyzed by SILAC-based MS. There was an inhibition of secretion of cargoes classified as class B upon ADF and cofilin1 knockdown (ratio between heavy and light peptides [H/L] > 1).