Table I.

Quantification of chromosomal morphology with SDs in HeLaI.2.11 siRNA-treated prometaphase spreads

siRNA Spreads scored Typical Telomere/arm Centromere 
GFP n = 66, 38, 202 51, 28, 168 (78% ± 4.8) 7, 2, 17 (8% ± 2.7) 8, 8, 17 (14% ± 6.3) 
TIN2 n = 63, 67, 200 30, 37, 84 (48% ± 6.6) 29, 25, 85 (42% ± 4.4) 4, 5, 31 (10% ± 5.0) 
SA1 n = 108, 112, 200 33, 38, 108 (40% ± 12.7) 57, 62, 73 (48% ± 10.2) 18, 12, 19 (12% ± 3.8) 
SA2 n = 106, 107, 200 26, 28, 80 (30% ± 8.5) 17, 1, 26 (10% ± 8.0) 63, 74, 94 (59% ± 11.1) 
siRNA Spreads scored Typical Telomere/arm Centromere 
GFP n = 66, 38, 202 51, 28, 168 (78% ± 4.8) 7, 2, 17 (8% ± 2.7) 8, 8, 17 (14% ± 6.3) 
TIN2 n = 63, 67, 200 30, 37, 84 (48% ± 6.6) 29, 25, 85 (42% ± 4.4) 4, 5, 31 (10% ± 5.0) 
SA1 n = 108, 112, 200 33, 38, 108 (40% ± 12.7) 57, 62, 73 (48% ± 10.2) 18, 12, 19 (12% ± 3.8) 
SA2 n = 106, 107, 200 26, 28, 80 (30% ± 8.5) 17, 1, 26 (10% ± 8.0) 63, 74, 94 (59% ± 11.1) 

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