Table I.

PEST sequences are highly conserved in Cavα1

Species Fragment Sequences PESTfind score 
Mouse PEST I 435-KGYLDWITQAEDIDPENEDEGMDEDK-460 8.45 
Rat PEST I 476-KGYLDWITQAEDIDPENEDEGMDEDK-501 8.45 
Human PEST I 446-KGYLDWITQAEDIDPENEDEGMDEEK-471 8.66 
Mouse PEST II 807-KSITADGESPPTTK-820 9.45 
Rat PEST II 848-KSITADGESPPTTK-861 9.45 
Mouse PEST III 837-HSNPDTAGEEDEEEPEMPVGPR-858 19.51 
Rat PEST III 878-HSNPDTAGEEDEEEPEMPVGPR-899 19.51 
Human PEST II 845-KSPYPNPETTGEEDEEEPEMPVGPR-869 20.26 
Mouse PEST IV 1,732-KTGNNQADTESPSH-1,745 5.5 
Rat PEST IV 1,772-KTGNNQADTESPSH-1,785 5.5 
Mouse PEST V 1,839-RMSEEAEYSEPSLLSTDMFSYQEDEH-1,865 5.86 
Human PEST IV 1,937-HDTEACSEPSLLSTEMLSYQDDENR-1,961 7.54 
Human PEST V 2,214-RGAPSEEELQDSR-2,226 7.71 

Occurrence of PEST sites within the amino acid sequence of Cavα1 from the mouse, rat, and human. Amino acid identity is underlined.

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