Table II.

Relative fold change of protein expression in OTCs with FsIL1ra compared with FCTRL

Cytokines/growth factors Fold increasea 
KGFb 5.47 ± 0.22c 
IL-6b 6.11 ± 0.31c 
IL-8 3.47 ± 0.06c 
IL-10 3.88 ± 0.15c 
IL-16 3.78 ± 0.41c 
GMCSFb 7.74 ± 0.31c 
CXCL1/GRO-α 2.67 ± 0.16d 
SDF-1 2.33 ± 0.07d 
I-309 4.57 ± 0.20c 
Eotaxin-2 6.19 ± 0.62c 
VEGF 0.22 ± 0.030d 
PIGF 0.25 ± 0.021d 
Cytokines/growth factors Fold increasea 
KGFb 5.47 ± 0.22c 
IL-6b 6.11 ± 0.31c 
IL-8 3.47 ± 0.06c 
IL-10 3.88 ± 0.15c 
IL-16 3.78 ± 0.41c 
GMCSFb 7.74 ± 0.31c 
CXCL1/GRO-α 2.67 ± 0.16d 
SDF-1 2.33 ± 0.07d 
I-309 4.57 ± 0.20c 
Eotaxin-2 6.19 ± 0.62c 
VEGF 0.22 ± 0.030d 
PIGF 0.25 ± 0.021d 

GRO-α, growth-related oncogene-α.

a

The intensities of signals were quantified by densitometry. Positive control included in the array blot was used to normalize and compare the results from different membranes. Values obtained from the control KCTRL/FCTRL OTC were arbitrarily assigned a value of 1. Values represent the mean fold increase as compared with control OTC (n = 3).

b

ChIP was performed on these genes using phospho–c-Jun antibody.

c

P < 0.01.

d

P < 0.1.

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