Relative fold change of protein expression in OTCs with FPPARβ/δ compared with FCTRL
| Cytokines/growth factors | Fold increasea |
| KGFb | 4.01 ± 0.11c |
| IL-6b | 5.56 ± 0.02c |
| IL-8b | 2.94 ± 0.14d |
| IL-10 | 2.13 ± 0.07c |
| IL-16 | 2.86 ± 0.11d |
| GMCSFb | 5.26 ± 0.10c |
| I-309 | 3.33 ± 0.16c |
| Eotaxin-2 | 3.03 ± 0.12c |
| VEGF | 0.25 ± 0.011d |
| PIGF | 0.33 ± 0.014d |
| Cytokines/growth factors | Fold increasea |
| KGFb | 4.01 ± 0.11c |
| IL-6b | 5.56 ± 0.02c |
| IL-8b | 2.94 ± 0.14d |
| IL-10 | 2.13 ± 0.07c |
| IL-16 | 2.86 ± 0.11d |
| GMCSFb | 5.26 ± 0.10c |
| I-309 | 3.33 ± 0.16c |
| Eotaxin-2 | 3.03 ± 0.12c |
| VEGF | 0.25 ± 0.011d |
| PIGF | 0.33 ± 0.014d |
The intensities of signals were quantified by densitometry. Positive control included in the array blot was used to normalize and compare the results from different membranes. Values obtained from the control KCTRL/FCTRL OTC were arbitrarily assigned a value of 1. Values represent the mean fold increase as compared with control OTC (n = 3).
mRNA expression levels of these genes were further verified by qPCR.
P < 0.01.
P < 0.1.