Table I. The effect of RanBPM loss on... | Rockefeller University Press

Table I.

The effect of RanBPM loss on cell number and size in the ovarian stem cell niche

Description/genotype	Isoform			Ratio mutant/control	t test p-value	Mean	SD
	Long	Short
GSCs per germarium
Mosaics	−	−	1.34^{^a}	1.7E-4	4.01	0.91	23
Nonmosaics	+	+			3.00	0.71	21
ΔN/ΔN	−	+	1.31^{^a}	4.3E-7	3.57	0.84	53
ΔN/CyO	+	+			2.73	0.61	37
null/null; arm > RanBPM^short	−	+	1.06	0.39	2.22	0.72	36
null/CyO; arm > RanBPM^short	+	+			2.09	0.52	33
CpCs per germarium
Mosaics	−	−	1.00	0.96	5.95	1.4	42
Nonmosaics	+	+			5.94	1.2	32
ΔN/ΔN	−	+	1.01	0.86	5.39	0.73	49
ΔN/CyO	+	+			5.36	0.64	36
null/ null; arm > RanBPM^short	−	+	0.81^{^a}	3.9E-7	4.08	0.71	38
null/CyO; arm > RanBPM^short	+	+			5.00	0.66	39
GSCs per CpC
null/null from mosaics	−	−	2.27^{^a}^{^b}	2.4E-5	1.09	0.52	58
All CpCs from mosaics	mixed	mixed	1.26^{^a}^{^b}	6.7E-3	0.63	0.17	152
+/+ from mosaics	+	+	0.96	0.80	0.48	0.35	94
null/CyO from nonmosaics	+	+			0.50	0.12	128
ΔN/ΔN	−	+	1.31^{^a}	1.1E-7	0.68	0.14	261
ΔN/CyO	+	+			0.52	0.11	193
null/null; arm > RanBPM^short	−	+	1.32^{^a}	5.2E-5	0.56	0.14	133
null/CyO; arm > RanBPM^short	+	+			0.42	0.11	164
CpC surface area (μm²)
null/null from mosaics	−	−	1.28^{^a}	4.0E-3	90.2	21.7	17
+/+ from mosaics	+	+			70.3	19.0	27
ΔN/ΔN	−	+	1.35^{^a}	1.4E-11	90.1	12.8	38
ΔN/CyO	+	+			66.5	12.0	34
null/null; arm > RanBPM^short	−	+	1.32^{^a}	6.4E-6	82.0	20.4	34
null/CyO; arm > RanBPM^short	+	+			62.2	7.3	19
Total niche cells
Mosaics	−	−	1.03	0.37	14.5	1.2	19
Nonmosaics	+	+			14.1	1.0	11
null/null; arm > RanBPM^short	−	+	0.94	1.3E-4	11.7	0.62	38
null/CyO; arm > RanBPM^short	+	+			12.4	0.88	39
Divisions per GSC
null/null from mosaics	−	−	0.93	0.78	0.26	0.26	92
+/+ from mosaics	+	+			0.28	0.27	63
ΔN/ΔN	−	+	1.10	0.46	0.43	0.21	189
ΔN/CyO	+	+			0.39	0.23	101
null/null; arm > RanBPM^short	−	+	1.47	0.22	0.33	0.38	80
null/CyO; arm > RanBPM^short	+	+			0.22	0.33	69
GSC surface area (μm²)
GSC attached to null/null CpC	−	−	1.04	0.31	356	41	21
GSC attached to wild-type CpC	+	+			341	53	22

Description/genotype	Isoform			Ratio mutant/control	t test p-value	Mean	SD
	Long	Short
GSCs per germarium
Mosaics	−	−	1.34^{^a}	1.7E-4	4.01	0.91	23
Nonmosaics	+	+			3.00	0.71	21
ΔN/ΔN	−	+	1.31^{^a}	4.3E-7	3.57	0.84	53
ΔN/CyO	+	+			2.73	0.61	37
null/null; arm > RanBPM^short	−	+	1.06	0.39	2.22	0.72	36
null/CyO; arm > RanBPM^short	+	+			2.09	0.52	33
CpCs per germarium
Mosaics	−	−	1.00	0.96	5.95	1.4	42
Nonmosaics	+	+			5.94	1.2	32
ΔN/ΔN	−	+	1.01	0.86	5.39	0.73	49
ΔN/CyO	+	+			5.36	0.64	36
null/ null; arm > RanBPM^short	−	+	0.81^{^a}	3.9E-7	4.08	0.71	38
null/CyO; arm > RanBPM^short	+	+			5.00	0.66	39
GSCs per CpC
null/null from mosaics	−	−	2.27^{^a}^{^b}	2.4E-5	1.09	0.52	58
All CpCs from mosaics	mixed	mixed	1.26^{^a}^{^b}	6.7E-3	0.63	0.17	152
+/+ from mosaics	+	+	0.96	0.80	0.48	0.35	94
null/CyO from nonmosaics	+	+			0.50	0.12	128
ΔN/ΔN	−	+	1.31^{^a}	1.1E-7	0.68	0.14	261
ΔN/CyO	+	+			0.52	0.11	193
null/null; arm > RanBPM^short	−	+	1.32^{^a}	5.2E-5	0.56	0.14	133
null/CyO; arm > RanBPM^short	+	+			0.42	0.11	164
CpC surface area (μm²)
null/null from mosaics	−	−	1.28^{^a}	4.0E-3	90.2	21.7	17
+/+ from mosaics	+	+			70.3	19.0	27
ΔN/ΔN	−	+	1.35^{^a}	1.4E-11	90.1	12.8	38
ΔN/CyO	+	+			66.5	12.0	34
null/null; arm > RanBPM^short	−	+	1.32^{^a}	6.4E-6	82.0	20.4	34
null/CyO; arm > RanBPM^short	+	+			62.2	7.3	19
Total niche cells
Mosaics	−	−	1.03	0.37	14.5	1.2	19
Nonmosaics	+	+			14.1	1.0	11
null/null; arm > RanBPM^short	−	+	0.94	1.3E-4	11.7	0.62	38
null/CyO; arm > RanBPM^short	+	+			12.4	0.88	39
Divisions per GSC
null/null from mosaics	−	−	0.93	0.78	0.26	0.26	92
+/+ from mosaics	+	+			0.28	0.27	63
ΔN/ΔN	−	+	1.10	0.46	0.43	0.21	189
ΔN/CyO	+	+			0.39	0.23	101
null/null; arm > RanBPM^short	−	+	1.47	0.22	0.33	0.38	80
null/CyO; arm > RanBPM^short	+	+			0.22	0.33	69
GSC surface area (μm²)
GSC attached to null/null CpC	−	−	1.04	0.31	356	41	21
GSC attached to wild-type CpC	+	+			341	53	22

Significant difference.

As compared with GSCs per CpC from the nonmosaic null/CyO control.

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