Summary of the results of the analysis of Sycp3−/−, Smc1β−/−, and Sycp3−/−Smc1β−/− mice
| Phenotype . | wt . | Smc1β−/− . | Sycp3−/− . | Sycp3−/−Smc1β−/− . | Comments . |
|---|---|---|---|---|---|
| Cohesin staining | Continuous | Continuous | Gaps | Gaps | DKO = Sypc3−/− |
| Core length (μm) | 11.93 | 7.28 | 22.9 | 18.35 | DKO not identical to any SKO |
| Loop length (mean) | Normal | Normal | Two times shorter | Normal | DKO = Smc1β−/− |
| Loop length (extensions) | No | Yes | No | Yes | DKO = Smc1β−/− |
| Asynapsis (%) | None | 9.3 | Rare | 11.63 | DKO = Smc1β−/− |
| Univalents in dictyate (%) | 0–0.7 | 3–12 | 3–14 | 9–20 | DKO = Sycp3−/− + Smc1β−/− |
| Oocyte loss | None | Some | Some | Faster | DKO = Sycp3−/− + Smc1β−/− |
| Phenotype . | wt . | Smc1β−/− . | Sycp3−/− . | Sycp3−/−Smc1β−/− . | Comments . |
|---|---|---|---|---|---|
| Cohesin staining | Continuous | Continuous | Gaps | Gaps | DKO = Sypc3−/− |
| Core length (μm) | 11.93 | 7.28 | 22.9 | 18.35 | DKO not identical to any SKO |
| Loop length (mean) | Normal | Normal | Two times shorter | Normal | DKO = Smc1β−/− |
| Loop length (extensions) | No | Yes | No | Yes | DKO = Smc1β−/− |
| Asynapsis (%) | None | 9.3 | Rare | 11.63 | DKO = Smc1β−/− |
| Univalents in dictyate (%) | 0–0.7 | 3–12 | 3–14 | 9–20 | DKO = Sycp3−/− + Smc1β−/− |
| Oocyte loss | None | Some | Some | Faster | DKO = Sycp3−/− + Smc1β−/− |