Table I. CCP size, as determined by... | Rockefeller University Press

Table I.

CCP size, as determined by negative-stain EM, varies with cargo, Dab2, and ARH expression levels

Adenovirus construct	Tet (ng/ml)	Adaptor protein expressed	CCP size (µm² ± SD)	n
Ventral cell surface
CD8/LDLR	1,000	Dab2	0.013 ± 0.03	20
CD8/LDLR	25	Dab2	0.45 ± 0.38^a	19
CD8/LDLR	0	Dab2	3.31 ± 2.49^b	8
CD8/LDLR	0	ARH	0.89 ± 0.54^c	27
Dorsal cell surface
TfnR	1,000	None	0.011 ± 0.004	51
TfnR	0	None	0.008 ± 0.003^d	82

Adenovirus construct	Tet (ng/ml)	Adaptor protein expressed	CCP size (µm² ± SD)	n
Ventral cell surface
CD8/LDLR	1,000	Dab2	0.013 ± 0.03	20
CD8/LDLR	25	Dab2	0.45 ± 0.38^a	19
CD8/LDLR	0	Dab2	3.31 ± 2.49^b	8
CD8/LDLR	0	ARH	0.89 ± 0.54^c	27
Dorsal cell surface
TfnR	1,000	None	0.011 ± 0.004	51
TfnR	0	None	0.008 ± 0.003^d	82

P < 0.001 relative to no CD8/LDLR expression (i.e. 1,000 ng/ml tet).

P < 0.001 relative to low levels of CD8/LDLR expression (i.e. 25 ng/ml tet).

P < 0.001 relative to Dab2 expression in the presence of high CD8/LDLR levels.

P < 0.001 relative to endogenous levels of TfnR expression (i.e. 1,000 ng/ml tet).