Table II.

Analysis of transport parameters for anterograde and retrograde syb-GFP containing vesicles in wild-type and mutant segmental nerves

Genotype Anterograde runs Retrograde runs 
 Velocity P-value Run length P-value n Velocity P-value Run length P-value n 
 µm ± SD  µm/s ± SD   µm/s ± SD  µm ± SD   
D42-GAL4; FSPWT 0.78 ± 0.13 NA 9.6 ± 2.5 NA 54 −0.72 ± 0.15 NA 9.2 ± 3.1 NA 80 
D42-GAL4/FSPAM 0.5 ± 0.17* <0.0001 6.8 ± 3.1* <0.0001 76 −0.55 ± 0.11* <0.0001 7.2 ± 2.5* <0.0001 97 
D42-GAL4; FSPGM 0.44 ± 0.15* <0.0001 6.1 ± 2.7* <0.0001 81 −0.48 ± 0.18* <0.0001 7.4 ± 3.3* <0.0001 135 
Genotype Anterograde runs Retrograde runs 
 Velocity P-value Run length P-value n Velocity P-value Run length P-value n 
 µm ± SD  µm/s ± SD   µm/s ± SD  µm ± SD   
D42-GAL4; FSPWT 0.78 ± 0.13 NA 9.6 ± 2.5 NA 54 −0.72 ± 0.15 NA 9.2 ± 3.1 NA 80 
D42-GAL4/FSPAM 0.5 ± 0.17* <0.0001 6.8 ± 3.1* <0.0001 76 −0.55 ± 0.11* <0.0001 7.2 ± 2.5* <0.0001 97 
D42-GAL4; FSPGM 0.44 ± 0.15* <0.0001 6.1 ± 2.7* <0.0001 81 −0.48 ± 0.18* <0.0001 7.4 ± 3.3* <0.0001 135 

Mean velocity and run length for both anterograde and retrograde moving particles are reduced in mutant β-spectrin larvae in comparison to wild type. Data shown represent mean ± SD. Asterisks denote statistical significant differences for mutant relative to wild type. NA, not applicable.

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