Activation of the SIN inhibits polarized cell growth
| Strain genotype | Number of nuclei (n) | Mean cell length ± SD | Mean cell diameter ± SD |
| (μm) | (μm) | ||
| wild type | n = 1 | 11.9 ± 1.8 | 2.93 ± 0.2 |
| n = 2 | 14.9 ± 0.817 | 2.95 ± 0.35 | |
| cdc3-124 cdc16-116 | n = 1 | 10.66 ± 2 | 4.62 ± 0.46 |
| n = 2 | 13.75 ± 2 | 4.7 ± 0.5 | |
| cdc15-140 cdc16-116 | n = 1 | 10.2 ± 2 | 6.46 ± 1.26 |
| n = 2 | 15 ± 1 | 6.086 ± 1.24 | |
| cdc3-124 cdc16-116 wee1-50 | n = 1 | 6.65 ± 0.85 | 4.81 ± 0.45 |
| n = 2 | 7.25 ± 1.4 | 4.43 ± 0.54 | |
| n = 4 | 9.6 ± 1.6 | 4.47 ± 0.61 | |
| cdc3-124 cdc16-116sid2-250 | n = 1 | N/A | N/A |
| n = 2 | 21.2 ± 1.75 | 3.47 ± 0.36 | |
| n = 4 | 26 ± 4 | 3.6 ± 0.434 | |
| cdc3-124 cdc16-116 sid2-250 orb6-25 | n = 1 | 7.86 ± 1.5 | 5.04 ± 0.41 |
| n = 2 | 13.23 ± 3 | 5.3 ± 0.365 | |
| n = 4 | 14.38 ± 1 | 8.23 ± 1.13 |
| Strain genotype | Number of nuclei (n) | Mean cell length ± SD | Mean cell diameter ± SD |
| (μm) | (μm) | ||
| wild type | n = 1 | 11.9 ± 1.8 | 2.93 ± 0.2 |
| n = 2 | 14.9 ± 0.817 | 2.95 ± 0.35 | |
| cdc3-124 cdc16-116 | n = 1 | 10.66 ± 2 | 4.62 ± 0.46 |
| n = 2 | 13.75 ± 2 | 4.7 ± 0.5 | |
| cdc15-140 cdc16-116 | n = 1 | 10.2 ± 2 | 6.46 ± 1.26 |
| n = 2 | 15 ± 1 | 6.086 ± 1.24 | |
| cdc3-124 cdc16-116 wee1-50 | n = 1 | 6.65 ± 0.85 | 4.81 ± 0.45 |
| n = 2 | 7.25 ± 1.4 | 4.43 ± 0.54 | |
| n = 4 | 9.6 ± 1.6 | 4.47 ± 0.61 | |
| cdc3-124 cdc16-116sid2-250 | n = 1 | N/A | N/A |
| n = 2 | 21.2 ± 1.75 | 3.47 ± 0.36 | |
| n = 4 | 26 ± 4 | 3.6 ± 0.434 | |
| cdc3-124 cdc16-116 sid2-250 orb6-25 | n = 1 | 7.86 ± 1.5 | 5.04 ± 0.41 |
| n = 2 | 13.23 ± 3 | 5.3 ± 0.365 | |
| n = 4 | 14.38 ± 1 | 8.23 ± 1.13 |
Average length and diameter measurements for cells with indicated genotype and the given number of nuclei are shown. SD, standard deviation. Measurements are not shown (N/A) if the strain did not arrest with a significant number of cells with the indicated number of nuclei. At least 100 cells were counted for each strain.