Table II.

Expression characteristics of transgenic clones after erythroid differentiation

BAC clone Gene analyzed Expression/copy from transgenea Total expression from transgenea Expression from endogenous locusb 
  % % % 
β-Globin 8d HBB/Hbb-b1 0.0089 1.4 10.3 
α-Globin 1c HBA/Hba-a1 0.26 160 4.3 
Dhfr 36 Dhfr 40 5,560 ND 
BAC clone Gene analyzed Expression/copy from transgenea Total expression from transgenea Expression from endogenous locusb 
  % % % 
β-Globin 8d HBB/Hbb-b1 0.0089 1.4 10.3 
α-Globin 1c HBA/Hba-a1 0.26 160 4.3 
Dhfr 36 Dhfr 40 5,560 ND 

Based on reverse transcription quantitative PCR data.

a

Relative to the endogenous locus in cells without the transgene.

b

Relative to expression in cells without the transgene.

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