Table I.

Pericentrin-interacting partners and associated functions.

Interacting partners Description: functions linked to pericentrin References 
Centrosome/microtubule   
    γ-tubulin γ-tubulin: microtubule nucleation/organization Knop and Schiebel, 1997; Dictenberg et al., 1998; Takahashi et al., 2002; Zimmerman et al., 2004  
    γ-TURC (GCP2, GCP3) γ-tubulin ring complex (γ-tubulin complex protein): microtubule nucleation/organization Knop and Schiebel, 1997; Takahashi et al., 2002; Zimmerman et al., 2004  
    PCM1 PCM protein: microtubule nucleation/organization Li et al., 2001  
    LIC Cytoplasmic dynein light intermediate chain: Microtubule nucleation/organization (motor protein) Purohit et al., 1999  
    AKAP450/CGNAP A-kinase anchoring protein/centrosomal and golgi N-kinase anchoring protein: microtubule nucleation/organization Takahashi et al., 2002  
    DISC-1 Disrupted in Schizophrenia: microtubule nucleation/organization Miyoshi et al., 2004; Shimizu et al., 2008  
Checkpoint   
    Chk1 Checkpoint kinase: DNA damage induced G2/M arrest regulation Tibelius et al., 2009  
Kinases   
    PKA Protein kinase A: cell signaling Diviani et al., 2000  
    PKCβII Protein kinase C: cell signaling Chen et al., 2004  
    BCR-ABL Oncogenic tyrosine kinase: cell signaling Patel and Gordon, 2009  
Nuclear   
    CHD3 Chromodomain helicase DNA-binding proteins: nuclear function, microtubule nucleation Sillibourne et al., 2007  
    CHD4 Chromodomain helicase DNA-binding proteins: nuclear function, microtubule nucleation Sillibourne et al., 2007  
Basal body/cilia   
    IFT Intraflagellar transport proteins: formation and function of cilia Jurczyk et al., 2004  
    PC2 Polycystin: cilia function/signaling Jurczyk et al., 2004  
Interacting partners Description: functions linked to pericentrin References 
Centrosome/microtubule   
    γ-tubulin γ-tubulin: microtubule nucleation/organization Knop and Schiebel, 1997; Dictenberg et al., 1998; Takahashi et al., 2002; Zimmerman et al., 2004  
    γ-TURC (GCP2, GCP3) γ-tubulin ring complex (γ-tubulin complex protein): microtubule nucleation/organization Knop and Schiebel, 1997; Takahashi et al., 2002; Zimmerman et al., 2004  
    PCM1 PCM protein: microtubule nucleation/organization Li et al., 2001  
    LIC Cytoplasmic dynein light intermediate chain: Microtubule nucleation/organization (motor protein) Purohit et al., 1999  
    AKAP450/CGNAP A-kinase anchoring protein/centrosomal and golgi N-kinase anchoring protein: microtubule nucleation/organization Takahashi et al., 2002  
    DISC-1 Disrupted in Schizophrenia: microtubule nucleation/organization Miyoshi et al., 2004; Shimizu et al., 2008  
Checkpoint   
    Chk1 Checkpoint kinase: DNA damage induced G2/M arrest regulation Tibelius et al., 2009  
Kinases   
    PKA Protein kinase A: cell signaling Diviani et al., 2000  
    PKCβII Protein kinase C: cell signaling Chen et al., 2004  
    BCR-ABL Oncogenic tyrosine kinase: cell signaling Patel and Gordon, 2009  
Nuclear   
    CHD3 Chromodomain helicase DNA-binding proteins: nuclear function, microtubule nucleation Sillibourne et al., 2007  
    CHD4 Chromodomain helicase DNA-binding proteins: nuclear function, microtubule nucleation Sillibourne et al., 2007  
Basal body/cilia   
    IFT Intraflagellar transport proteins: formation and function of cilia Jurczyk et al., 2004  
    PC2 Polycystin: cilia function/signaling Jurczyk et al., 2004  

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