Table 2.
Analyses of patterning defects in retinas
GenotypePatterning errors per data pointTotal errors per data point (ommatidium + surrounding lattice)
Cone cell defects (1)1° cell defects (2)Ommatidial misorientations (3)Bristle defects (4)3° cell defects (5)Errors in lattice cell number (6)
MeanSDMeanSDMeanSDMeanSDMeanSDMeanSDMeanSDSEComparison with cnoWT-GFP (P value)
w1118 0.00 0.00 0.02 0.18 0.00 0.00 0.28 0.45 0.10 0.30 0.21 0.46 0.61 0.94 0.09 0.8087 
w1118; cnoWT-GFP 0.01 0.09 0.01 0.09 0.00 0.00 0.27 0.48 0.07 0.25 0.22 0.45 0.58 0.94 0.09  
w1118; cno△PDZ-GFP 0.30 0.62 0.21 0.52 0.08 0.27 0.69 0.72 0.68 0.78 0.65 0.77 2.61 2.40 0.22 <0.0001 
w1118; cno△FAB-GFP 0.13 0.40 0.16 0.61 0.02 0.13 0.34 0.56 0.16 0.43 0.23 0.91 1.03 1.68 0.15 0.0106 
GenotypePatterning errors per data pointTotal errors per data point (ommatidium + surrounding lattice)
Cone cell defects (1)1° cell defects (2)Ommatidial misorientations (3)Bristle defects (4)3° cell defects (5)Errors in lattice cell number (6)
MeanSDMeanSDMeanSDMeanSDMeanSDMeanSDMeanSDSEComparison with cnoWT-GFP (P value)
w1118 0.00 0.00 0.02 0.18 0.00 0.00 0.28 0.45 0.10 0.30 0.21 0.46 0.61 0.94 0.09 0.8087 
w1118; cnoWT-GFP 0.01 0.09 0.01 0.09 0.00 0.00 0.27 0.48 0.07 0.25 0.22 0.45 0.58 0.94 0.09  
w1118; cno△PDZ-GFP 0.30 0.62 0.21 0.52 0.08 0.27 0.69 0.72 0.68 0.78 0.65 0.77 2.61 2.40 0.22 <0.0001 
w1118; cno△FAB-GFP 0.13 0.40 0.16 0.61 0.02 0.13 0.34 0.56 0.16 0.43 0.23 0.91 1.03 1.68 0.15 0.0106 

The following defects were scored in 118 data points (illustrated in Fig. 9) per genotype: (1) errors in cone cell number and arrangement; (2) incorrect number, relative size and junctional integrity of 1° cells; (3) incorrect orientation of ommatidial core (likely due to earlier mis-rotation); (4) errors in bristle placement and number; (5) incorrect specification of 3° cells; (6) additional or missing lattice cells (2° cells + 3° cells).

[ViewLarge]
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal