Table 3.
The number of circulating blood cells in WT, DREAM KO, and BM chimeric mice
WBC (103/µl)NE (103/µl)LY (103/µl)MO (103/µl)RBC (106/µl)PLT (106/µl)MPV (fl)
WT (CD45.1) 5.2 ± 2.7 0.8 ± 0.2 4.0 ± 1.5 0.2 ± 0.0 7.4 ± 1.7 882 ± 164 5.9 ± 0.9 
DREAM KO 3.6 ± 0.8 0.7 ± 0.2 2.9 ± 1.3 0.1 ± 0.0 7.5 ± 1.4 976 ± 193 5.9 ± 1.0 
BM chimeric mice 5.4 ± 1.7 0.9 ± 0.2 4.2 ± 1.7 0.3 ± 0.1 8.8 ± 1.0 1,215 ± 219 6.3 ± 1.0 
WBC (103/µl)NE (103/µl)LY (103/µl)MO (103/µl)RBC (106/µl)PLT (106/µl)MPV (fl)
WT (CD45.1) 5.2 ± 2.7 0.8 ± 0.2 4.0 ± 1.5 0.2 ± 0.0 7.4 ± 1.7 882 ± 164 5.9 ± 0.9 
DREAM KO 3.6 ± 0.8 0.7 ± 0.2 2.9 ± 1.3 0.1 ± 0.0 7.5 ± 1.4 976 ± 193 5.9 ± 1.0 
BM chimeric mice 5.4 ± 1.7 0.9 ± 0.2 4.2 ± 1.7 0.3 ± 0.1 8.8 ± 1.0 1,215 ± 219 6.3 ± 1.0 

The blood was obtained from 8–10-wk-old male WT (B6.SJL-PtprcaPepcb/BoyJ, a C57BL/6 congenic strain [CD45.1]) and DREAM KO mice and from BM chimeric mice at 6 wk after transplantation of an equal number of WT and KO BM cells into WT (CD45.1) mice. Blood cells were counted using HEMAVET 950 (Drew Scientific). Data represent the mean ± SD (n = 6 mice per group). WBC, white blood cells; NE, neutrophils; LY, lymphocytes; MO, monocytes; PLT, platelets; MPV, mean platelet volume.

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