Table 2.
Clinical features of T. marneffei infections in patients with anti–IFN-γ autoantibodies
Clinical featuresNumber (n = 55)Percentage (%)
Symptoms/signs 
Fever 47 85.5 
Leukocytosis 46 83.6 
Cough 44 80.0 
Weight loss 43 78.2 
Lymphadenopathy 42 76.4 
Anemia 34 61.8 
Thrombocytosis 30 54.5 
Cutaneous or subcutaneous lesion 28 50.9 
Misdiagnosed as TB 28 50.9 
Malaise 25 45.5 
Arthritis or arthralgia 19 34.5 
Lymphopenia 13 23.6 
Abdominal pain or diarrhea 11 20.0 
Chest pain 11 20.0 
Dyspnea 11 20.0 
Hepatomegaly 16.4 
Thrombocytopenia 12.7 
Splenomegaly 10.9 
Hemoptysis 9.1 
Osteomyelitis 3.6 
Organ involvement 
Lung/pleura 55 100.0 
Lymph node 43 78.2 
Skin 26 47.3 
Bone/joints 13 23.6 
Liver 14.5 
Spleen 9.1 
Clinical featuresNumber (n = 55)Percentage (%)
Symptoms/signs 
Fever 47 85.5 
Leukocytosis 46 83.6 
Cough 44 80.0 
Weight loss 43 78.2 
Lymphadenopathy 42 76.4 
Anemia 34 61.8 
Thrombocytosis 30 54.5 
Cutaneous or subcutaneous lesion 28 50.9 
Misdiagnosed as TB 28 50.9 
Malaise 25 45.5 
Arthritis or arthralgia 19 34.5 
Lymphopenia 13 23.6 
Abdominal pain or diarrhea 11 20.0 
Chest pain 11 20.0 
Dyspnea 11 20.0 
Hepatomegaly 16.4 
Thrombocytopenia 12.7 
Splenomegaly 10.9 
Hemoptysis 9.1 
Osteomyelitis 3.6 
Organ involvement 
Lung/pleura 55 100.0 
Lymph node 43 78.2 
Skin 26 47.3 
Bone/joints 13 23.6 
Liver 14.5 
Spleen 9.1 

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