Table 1. Luminal membrane permeability... | Rockefeller University Press

Table 1.

Luminal membrane permeability assignment for Na⁺ and K⁺ permeabilities

	CNTe		CNTas
	Na⁺	K+	Na⁺	K+
Control
Whole-cell current (pA/cell)	660	−430	30	−260
Luminal fluxes (fmol/cell)	6.8	−4.5	0.3	−2.7
Epithelial fluxes (nmol/s/cm²)^a	6.1	−3.9	0.3	−2.4
H_MI₀ (cm³/s/cm² epithelium) × 10⁵	16.5	2.8	0.13	1.8
High-K diet
Whole-cell current (pA/cell)	770	−1,250	480	−780
Luminal fluxes (fmol/cell)	8.0	−13.0	5.0	−8.1
Epithelial fluxes (nmol/s/cm²)^a	7.1	−11.5	4.4	−7.2
H_MI₀ (cm³/s/cm² epithelium) × 10⁵	24.9	8.5	2.2	5.3
Low-K diet
Whole-cell current (pA/cell)	360	−180
Luminal fluxes (fmol/cell)	3.7	−1.9
Epithelial fluxes (nmol/s/cm²)^a	3.3	−1.7
H_MI₀ (cm³/s/cm² epithelium) × 10⁵	8.5	1.2	0.13	1.8

	CNTe		CNTas
	Na⁺	K+	Na⁺	K+
Control
Whole-cell current (pA/cell)	660	−430	30	−260
Luminal fluxes (fmol/cell)	6.8	−4.5	0.3	−2.7
Epithelial fluxes (nmol/s/cm²)^a	6.1	−3.9	0.3	−2.4
H_MI₀ (cm³/s/cm² epithelium) × 10⁵	16.5	2.8	0.13	1.8
High-K diet
Whole-cell current (pA/cell)	770	−1,250	480	−780
Luminal fluxes (fmol/cell)	8.0	−13.0	5.0	−8.1
Epithelial fluxes (nmol/s/cm²)^a	7.1	−11.5	4.4	−7.2
H_MI₀ (cm³/s/cm² epithelium) × 10⁵	24.9	8.5	2.2	5.3
Low-K diet
Whole-cell current (pA/cell)	360	−180
Luminal fluxes (fmol/cell)	3.7	−1.9
Epithelial fluxes (nmol/s/cm²)^a	3.3	−1.7
H_MI₀ (cm³/s/cm² epithelium) × 10⁵	8.5	1.2	0.13	1.8

Assumes 500 cells/mm of tubule and tubular inner diameter of 18 µm.

Transcellular fluxes refer to epithelial area.