| Methods | Slow | Intermediate | Fast | Very fast |
|---|---|---|---|---|
| Sinusoidal analysis | Process A | Process B | Process C | Y∞ |
| (Tension transients) | Oscillatory work | |||
| Phase advance | Phase delay | Phase advance | ||
| Isometric step | Phase 4 | Phase 3 | Phase 2 | Phase 1 |
| (Tension transients) | Delayed tension | |||
| Exponential advance | Exponential delay | Exponential advance | ||
| Isotonic step (length transients) | Steady velocity of shortening phase | Phase 3 with the rate constant r3 | Phase 2 with the rate constant r2 | Phase 1 |
| Mechanisms in CB cycle | Step 6 (linear work production) | Step 4 (force generation, oscillatory work production) | Step 2 (CB detachment after ATP binding) |
| Methods | Slow | Intermediate | Fast | Very fast |
|---|---|---|---|---|
| Sinusoidal analysis | Process A | Process B | Process C | |
| (Tension transients) | Oscillatory work | |||
| Phase advance | Phase delay | Phase advance | ||
| Isometric step | Phase 4 | Phase 3 | Phase 2 | Phase 1 |
| (Tension transients) | Delayed tension | |||
| Exponential advance | Exponential delay | Exponential advance | ||
| Isotonic step (length transients) | Steady velocity of shortening phase | Phase 3 with the rate constant | Phase 2 with the rate constant | Phase 1 |
| Mechanisms in CB cycle | Step 6 (linear work production) | Step 4 (force generation, oscillatory work production) | Step 2 (CB detachment after ATP binding) |
The correlation between processes in sinusoidal analysis and phases in step analysis is theoretically perfect (Kawai and Brandt, 1980), and the measurements are carried out under the isometric condition. The correlation between tension transients and length transients is only approximate. The general rule is that a fast process in one method corresponds to a fast process in the other, but the correlation becomes weaker as the process becomes slower. The polarity of process A (phase 4) and process C (phase 2) is positive, and the polarity of process B (phase 3) is negative (Eq. 4). For the length transients, terminology used previously (Caremani et al., 2013) is employed.
As a benefit of your subscription, you can share temporary access to restricted articles.
Each link will stop working after 30 days or 10 uses. You may create up to 10 links in a 30 day period.
Please sign in to your personal account to gift article access.
As a benefit of your subscription, you can share temporary access to restricted articles.
Each link will stop working after 30 days or 10 uses. You may create up to 10 links in a 30 day period.
Gift articles remaining: --
Each link will stop working after 30 days or 10 uses. You may create up to 10 links in a 30 day period.
Gift articles remaining: --
As a benefit of your subscription, you can share temporary access to restricted articles.
Each link will stop working after 30 days or 10 uses.
You have reached the limit of 10 links within a 30 day period.
Sharing content requires targeting cookies to be enabled. Please update your cookie preferences to use this feature.