Table 1. Comparison of oligomeric... | Rockefeller University Press

Table 1.

Comparison of oligomeric configuration with pore constriction diameter

ATP-permeant channel	Oligomeric configuration	Pore constriction diameter (Å)	Reference
VDAC	Monomer (β barrel)	25	Colombini, 2012
Cx26	Hexamer	14 (open), 6 (closed)	Maeda et al., 2009; Nielsen et al., 2012
Cx31.3	Hexamer	8 (closed?)	Lee et al., 2020
Cx43	Hexamer	25 (open), 18 (closed)	Nielsen et al., 2012
Cx46	Hexamer	14	Myers et al., 2018; Flores et al., 2020
VRAC	Hexamer	12–14 (open), 2–5 (closed)	Deneka et al., 2018; Kasuya et al., 2018; Kefauver et al., 2018; Osei-Owusu et al., 2018
Panx1	Heptamer	9	Deng et al., 2020; Jin et al., 2020; Michalski et al., 2020; Mou et al., 2020; Qu et al., 2020; Ruan et al., 2020
Innexin6	Octamer	18	Oshima et al., 2016
CALHM1	Octamer	19.5	Syrjanen et al., 2020
CALHM2	Undecamer	50 (open), 23 (inhibited)	Choi et al., 2019
CALHM4	Decamer, undecamer	20 (without current), 30 (without current)	Drożdżyk et al., 2020

ATP-permeant channel	Oligomeric configuration	Pore constriction diameter (Å)	Reference
VDAC	Monomer (β barrel)	25	Colombini, 2012
Cx26	Hexamer	14 (open), 6 (closed)	Maeda et al., 2009; Nielsen et al., 2012
Cx31.3	Hexamer	8 (closed?)	Lee et al., 2020
Cx43	Hexamer	25 (open), 18 (closed)	Nielsen et al., 2012
Cx46	Hexamer	14	Myers et al., 2018; Flores et al., 2020
VRAC	Hexamer	12–14 (open), 2–5 (closed)	Deneka et al., 2018; Kasuya et al., 2018; Kefauver et al., 2018; Osei-Owusu et al., 2018
Panx1	Heptamer	9	Deng et al., 2020; Jin et al., 2020; Michalski et al., 2020; Mou et al., 2020; Qu et al., 2020; Ruan et al., 2020
Innexin6	Octamer	18	Oshima et al., 2016
CALHM1	Octamer	19.5	Syrjanen et al., 2020
CALHM2	Undecamer	50 (open), 23 (inhibited)	Choi et al., 2019
CALHM4	Decamer, undecamer	20 (without current), 30 (without current)	Drożdżyk et al., 2020