Parameters of functional dependencies of CRE characteristics on RYR coupling strength φ
Weight factor α = 0.67 ± 0.002
.
.
Fmax
.
K
.
n
.
0.40 ± 0.004
0.019 ± 1E-4
3.69 ± 0.05
Fnq(φ)
0.87 ± 0.003
0.012 ± 5E-5
2.07 ± 0.01
Fs(φ)
0.78 ± 0.002
0.018 ± 5E-5
4.87 ± 0.02
Weight factor α = 0.67 ± 0.002
.
.
Fmax
.
K
.
n
.
0.40 ± 0.004
0.019 ± 1E-4
3.69 ± 0.05
Fnq(φ)
0.87 ± 0.003
0.012 ± 5E-5
2.07 ± 0.01
Fs(φ)
0.78 ± 0.002
0.018 ± 5E-5
4.87 ± 0.02
See Fig. 7 B. The parameters Fmax, K, and n of fitting functions Fnq(φ), and Fs(φ) are defined by Eq. 9, and the weight factor α by Eq. 8. R2 = 0.98; 10,108 data points.