Table 1.
Conductance levels, open-time events, and shut-time events for GluA2 receptor alone, in tandem with γ8, and in the presence of CTZ
Conductance level (pS)GluA2GluA2/γ8GluA2 + CTZ
7.0 ± 0.4 (71.0 ± 2.0%) 7.0 ± 1.0 (3.5 ± 0.5%)a 7.0 ± 0.5 (4.5 ± 0.25%)a 
14.0 ± 1.9 (21.0 ± 2.0%) 14.0 ± 0.8 (10.5 ± 1%)a 14.0 ± 0.5 (12.5 ± 0.6%)a 
22.0 ± 0.9 (3.5 ± 1.1%) 22.0 ± 1.4 (16.0 ± 4.0%)a 22.0 ± 1.7 (19.0 ± 9.0%)a 
— 37.0 ± 1.5 (75.0 ± 12.0%) 37.0 ± 2.1 (72.0 ± 10.0%) 
Mean open period (ms) 2.0 ± 0.4 17.0 ± 1.6b 31.4 ± 1.6a 
Open events    
τ1 1.0 ± 0.3 (89.0 ± 3.0%) 0.8 ± 0.1 (78.0 ± 11.0%) 0.5 ± 0.15 (20 ± 6.0%) 
τ2 8.2 ± 2.2 (10.0 ± 2.0%) 9.0 ± 5.0 (13.0 ± 5.0%) 38.0 ± 5.0 (80.0 ± 13%) 
τ3 — 81.0 ± 16.0 (9.0 ± 4.0%) — 
Mean shut period (ms) 479.0 ± 57.0 36.8 ± 10.5a 10.3 ± 0.7a 
Shut events    
τ1 5.6 ± 0.3 (27.2 ± 4.1%) 0.7 ± 0.3 (70 ± 10.0%) 0.7 ± 0.1 (49.2 ± 4.5%) 
τ2 203.5 ± 14.0 (50.0 ± 9.0%) 4.6 ± 1.4 (15 ± 5.0%) 5.0 ± 1.0 (34.2 ± 7.6%) 
τ3 1,093.0 ± 162.0 (22.0 ± 5.0%) 60.0 ± 10.0 (11.0 ± 7.0%) 48.0 ± 5.0 (16.6 ± 3.6%) 
τ4 — 527.0 ± 183.0 (5.0 ± 3.0%) — 
Conductance level (pS)GluA2GluA2/γ8GluA2 + CTZ
7.0 ± 0.4 (71.0 ± 2.0%) 7.0 ± 1.0 (3.5 ± 0.5%)a 7.0 ± 0.5 (4.5 ± 0.25%)a 
14.0 ± 1.9 (21.0 ± 2.0%) 14.0 ± 0.8 (10.5 ± 1%)a 14.0 ± 0.5 (12.5 ± 0.6%)a 
22.0 ± 0.9 (3.5 ± 1.1%) 22.0 ± 1.4 (16.0 ± 4.0%)a 22.0 ± 1.7 (19.0 ± 9.0%)a 
— 37.0 ± 1.5 (75.0 ± 12.0%) 37.0 ± 2.1 (72.0 ± 10.0%) 
Mean open period (ms) 2.0 ± 0.4 17.0 ± 1.6b 31.4 ± 1.6a 
Open events    
τ1 1.0 ± 0.3 (89.0 ± 3.0%) 0.8 ± 0.1 (78.0 ± 11.0%) 0.5 ± 0.15 (20 ± 6.0%) 
τ2 8.2 ± 2.2 (10.0 ± 2.0%) 9.0 ± 5.0 (13.0 ± 5.0%) 38.0 ± 5.0 (80.0 ± 13%) 
τ3 — 81.0 ± 16.0 (9.0 ± 4.0%) — 
Mean shut period (ms) 479.0 ± 57.0 36.8 ± 10.5a 10.3 ± 0.7a 
Shut events    
τ1 5.6 ± 0.3 (27.2 ± 4.1%) 0.7 ± 0.3 (70 ± 10.0%) 0.7 ± 0.1 (49.2 ± 4.5%) 
τ2 203.5 ± 14.0 (50.0 ± 9.0%) 4.6 ± 1.4 (15 ± 5.0%) 5.0 ± 1.0 (34.2 ± 7.6%) 
τ3 1,093.0 ± 162.0 (22.0 ± 5.0%) 60.0 ± 10.0 (11.0 ± 7.0%) 48.0 ± 5.0 (16.6 ± 3.6%) 
τ4 — 527.0 ± 183.0 (5.0 ± 3.0%) — 

Percentage of occurrence for each level or event is shown next to its value in parentheses. The error in the lifetimes is the SE of the fit. The table is related to Figs. 1 and 3.

a

P < 0.001 compared with GluA2.

b

P < 0.01 compared with GluA2.

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