Table 3.
Echocardiography parameters of transgenic mice
Number of animals (n)Body weight (g)LVID;LVID;LVPW;LVPW;LVAW;LVAW;
diastole (mm)systole (mm)diastole (mm)systole (mm)diastole (mm)systole (mm)
Control n = 14 33 ± 2 4.91 ± 0.19 3.94 ± 0.21 0.67 ± 0.02 0.91 ± 0.04 0.67 ± 0.02 0.90 ± 0.04 
cMyBP-C 3tSD n = 12 29 ± 2 4.45 ± 0.23 3.42 ± 0.27a 0.67 ± 0.01 0.89 ± 0.05 0.68 ± 0.01 0.88 ± 0.03 
cMyBP-C 3tSA n = 11 30 ± 2 5.05 ± 0.10 4.41 ± 0.11 0.66 ± 0.01 0.77 ± 0.01 0.65 ± 0.01 0.76 ± 0.01 
cMyBP-C KO n = 11 26 ± 1 4.83 ± 0.21 4.17 ± 0.21 0.70 ± 0.04 0.86 ± 0.06 0.69 ± 0.03 0.80 ± 0.03 
Number of animals (n)Body weight (g)LVID;LVID;LVPW;LVPW;LVAW;LVAW;
diastole (mm)systole (mm)diastole (mm)systole (mm)diastole (mm)systole (mm)
Control n = 14 33 ± 2 4.91 ± 0.19 3.94 ± 0.21 0.67 ± 0.02 0.91 ± 0.04 0.67 ± 0.02 0.90 ± 0.04 
cMyBP-C 3tSD n = 12 29 ± 2 4.45 ± 0.23 3.42 ± 0.27a 0.67 ± 0.01 0.89 ± 0.05 0.68 ± 0.01 0.88 ± 0.03 
cMyBP-C 3tSA n = 11 30 ± 2 5.05 ± 0.10 4.41 ± 0.11 0.66 ± 0.01 0.77 ± 0.01 0.65 ± 0.01 0.76 ± 0.01 
cMyBP-C KO n = 11 26 ± 1 4.83 ± 0.21 4.17 ± 0.21 0.70 ± 0.04 0.86 ± 0.06 0.69 ± 0.03 0.80 ± 0.03 

Values are means ± SEM.

LVAW, left ventricular anterior wall; LVID, left ventricular inner diameter; LVPW, left ventricular posterior wall.

a

P < 0.05 versus cMyBP-C 3tSA.

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