Table 1.
Transgenic mouse permeabilized cardiac myocyte preparations at long SL
Cardiac myocyte preparationsLength (µm)Width (µm)SL (µm)Passive tension (kN·m−2)Maximum force (µN)Maximum tension (kN·m−2)pCa for half-max. tensionRelative tension half-max. pCa
Control (n = 5) n = 6 128 ± 14 22 ± 2 2.22 ± 0.02 2.29 ± 0.27 16.5 ± 1.9 66 ± 13 5.92 ± 0.04 0.47 ± 0.03 
cMyBP-C 3tSD (n = 7) n = 8 140 ± 10 22 ± 2 2.27 ± 0.02 1.79 ± 0.21 16.3 ± 2.0 63 ± 6 5.95 ± 0.03 0.47 ± 0.02 
cMyBP-C 3tSA (n = 5) n = 7 122 ± 9 21 ± 1 2.24 ± 0.02 1.97 ± 0.36 12.7 ± 0.9 53 ± 7 5.94 ± 0.05 0.52 ± 0.02 
cMyBP-C KO (n = 6) n = 7 150 ± 17 25 ± 2 2.22 ± 0.02 1.66 ± 0.16 16.8 ± 1.8 51 ± 7 5.91 ± 0.03 0.48 ± 0.03 
Cardiac myocyte preparationsLength (µm)Width (µm)SL (µm)Passive tension (kN·m−2)Maximum force (µN)Maximum tension (kN·m−2)pCa for half-max. tensionRelative tension half-max. pCa
Control (n = 5) n = 6 128 ± 14 22 ± 2 2.22 ± 0.02 2.29 ± 0.27 16.5 ± 1.9 66 ± 13 5.92 ± 0.04 0.47 ± 0.03 
cMyBP-C 3tSD (n = 7) n = 8 140 ± 10 22 ± 2 2.27 ± 0.02 1.79 ± 0.21 16.3 ± 2.0 63 ± 6 5.95 ± 0.03 0.47 ± 0.02 
cMyBP-C 3tSA (n = 5) n = 7 122 ± 9 21 ± 1 2.24 ± 0.02 1.97 ± 0.36 12.7 ± 0.9 53 ± 7 5.94 ± 0.05 0.52 ± 0.02 
cMyBP-C KO (n = 6) n = 7 150 ± 17 25 ± 2 2.22 ± 0.02 1.66 ± 0.16 16.8 ± 1.8 51 ± 7 5.91 ± 0.03 0.48 ± 0.03 

Values are means ± SEM.

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