| A-i, impermeant intracellular anion (= Donnan effector) |
| AChR, acetylcholine receptor (i.e., SMFs’ nicotinic cation-selective channel) |
| amol/s, attomoles/second (10-18 mole/second) |
| AP, action potential (Vm(t)) |
| ATP, adenosine triphosphate |
| Cm, total membrane capacitance of the cell model |
| CD, Charge Difference (all models are thus designated: CN-CD, MN-CD, SM-CD, LA-CD, WD-CD) |
| CN-CD, Cortical Neuron-CD (MODEL; the “parent” model; see Table 2) |
| DE, Donnan equilibrium |
| DMD, Duchenne muscular dystrophy |
| EionX, Nernst potential for named ion |
| EPSC, excitatory post-synaptic current (for SMFs, the endplate current) |
| GHK, Goldman–Hodgkin–Katz (electrodiffusive fluxes; open channel I/V relations) |
| H-H, Hodgkin-Huxley (for V-gated channels: non-dimensional parameters, m,h,n) |
| IionX, currents through channels permeant to ionX (or, if gated, then INav, IKv) |
| INaKpump, INa,pump, IK,pump, ImaxNaKpump (below, see 3Na+/2K+-ATPase & max) |
| Kv, voltage-gated potassium channel (or delayed rectifier) |
| LA-CD, Low ATPase-CD (MODEL;a low pump-strength SM-CD variant; see Table 2) |
| max, 100% levels for pump: maximal ATP-consumption (amol/s) or ImaxNaKpump |
| mdx, dystrophin-minus mouse |
| MN-CD,Minimal Neuron-CD (MODEL; CN-CD without co-transporter; see Table 2) |
| MRI, magnetic resonance imaging |
| 3Na+/2K+-ATPase, “the pump”; as an electrogenic ATP-consuming enzyme, it generates… unidirectional ((efflux) INa,pump + (influx) IK,pump) = hyperpolarizing INaKpump |
| NAi , the quantity (attomoles) of cytoplasmic impermeant anions |
| Nav, voltage-gated sodium channel |
| Nav-CLS, coupled left-shift (of Nav channel gating) |
| Pcatleak, permeability of cation-selective channel |
| PCl, PNa, PK, permeabilities of always-open (“background,” “resting,” “leak” channels selective for Cl-, Na+, K+ (thus, PNa:PK:PCl -- relative values in a specified membrane) |
| PH2O, membrane water permeability |
| PNav (or Kv or Clv), for V-gated channels permeability equivalents to gmax |
| P-L/D, Pump-Leak/Donnan |
| ROS, reactive oxygen species |
| SA, surface area (directly proportional to model parameter Cm) |
| SM-CD, Skeletal Muscle-CD (MODEL; see Table 2) |
| SMF, skeletal muscle fiber |
| UKCl, K/Cl cotransporter – maximal flux capacity |
| Vm, Vrest, membrane potential, resting (steady-state) potential |
| Vol, volume (Volcell is the corresponding cell model parameter) |
| WD-CD, Weak Donnan-CD (MODEL; an SM-CD analog, see Table 2) |
| A-i, impermeant intracellular anion (= Donnan effector) |
| AChR, acetylcholine receptor (i.e., SMFs’ nicotinic cation-selective channel) |
| amol/s, attomoles/second (10-18 mole/second) |
| AP, action potential (Vm(t)) |
| ATP, adenosine triphosphate |
| Cm, total membrane capacitance of the cell model |
| CD, Charge Difference (all models are thus designated: CN-CD, MN-CD, SM-CD, LA-CD, WD-CD) |
| CN-CD, Cortical Neuron-CD (MODEL; the “parent” model; see Table 2) |
| DE, Donnan equilibrium |
| DMD, Duchenne muscular dystrophy |
| EionX, Nernst potential for named ion |
| EPSC, excitatory post-synaptic current (for SMFs, the endplate current) |
| GHK, Goldman–Hodgkin–Katz (electrodiffusive fluxes; open channel I/V relations) |
| H-H, Hodgkin-Huxley (for V-gated channels: non-dimensional parameters, m,h,n) |
| IionX, currents through channels permeant to ionX (or, if gated, then INav, IKv) |
| INaKpump, INa,pump, IK,pump, ImaxNaKpump (below, see 3Na+/2K+-ATPase & max) |
| Kv, voltage-gated potassium channel (or delayed rectifier) |
| LA-CD, Low ATPase-CD (MODEL;a low pump-strength SM-CD variant; see Table 2) |
| max, 100% levels for pump: maximal ATP-consumption (amol/s) or ImaxNaKpump |
| mdx, dystrophin-minus mouse |
| MN-CD,Minimal Neuron-CD (MODEL; CN-CD without co-transporter; see Table 2) |
| MRI, magnetic resonance imaging |
| 3Na+/2K+-ATPase, “the pump”; as an electrogenic ATP-consuming enzyme, it generates… unidirectional ((efflux) INa,pump + (influx) IK,pump) = hyperpolarizing INaKpump |
| NAi , the quantity (attomoles) of cytoplasmic impermeant anions |
| Nav, voltage-gated sodium channel |
| Nav-CLS, coupled left-shift (of Nav channel gating) |
| Pcatleak, permeability of cation-selective channel |
| PCl, PNa, PK, permeabilities of always-open (“background,” “resting,” “leak” channels selective for Cl-, Na+, K+ (thus, PNa:PK:PCl -- relative values in a specified membrane) |
| PH2O, membrane water permeability |
| PNav (or Kv or Clv), for V-gated channels permeability equivalents to gmax |
| P-L/D, Pump-Leak/Donnan |
| ROS, reactive oxygen species |
| SA, surface area (directly proportional to model parameter Cm) |
| SM-CD, Skeletal Muscle-CD (MODEL; see Table 2) |
| SMF, skeletal muscle fiber |
| UKCl, K/Cl cotransporter – maximal flux capacity |
| Vm, Vrest, membrane potential, resting (steady-state) potential |
| Vol, volume (Volcell is the corresponding cell model parameter) |
| WD-CD, Weak Donnan-CD (MODEL; an SM-CD analog, see Table 2) |