| Toxin (company) . | Number of mice (number of NMJs) . | Results (before vs. after toxin) . | Nested ANOVA (P value) . |
|---|---|---|---|
| Iberiotoxin (Sigma-Aldrich), 400 nM | 4 (43 before, 51 after) | Quantal content, 58.8 ± 2.6 vs. 60.0 ± 2.4; mFreq, 2.8 ± 0.7 vs. 4.0 ± 0.6 | Quantal content, 0.825; mFreq, 0.224 |
| Iberiotoxin (Cayman), 400 nM | 3 (37 before, 50 after) | Quantal content, 41.5 ± 2.7 vs. 41.7 ± 2.2; mFreq, 3.58 ± 0.6 vs. 4.7 ± 0.5 | Quantal content, 0.959; mFreq, 0.121 |
| Charybdotoxin (Alomone), 400 nM | 6 (70 before, 96 after) | Quantal content, 57.8 ± 1.8 vs. 55.3 ± 1.5; mFreq, 4.8 ± 0.7 vs. 4.8 ± 0.6 | Quantal content, 0.287; mFreq, 0.926 |
| Charybdotoxin (Cayman), 400 nM | 3 (45 before, 56 after) | Quantal content, 57.9 ± 2.7 vs. 56.2 ± 2.4; mFreq, 6.1 ± 0.8 vs. 7.8 ± 0.7 | Quantal content, 0.628; mFreq, 0.119 |
| Paxilline (Sigma-Aldrich), 10 µM | 5 (55 before, 63 after) | Quantal content, 48.6 ± 1.5 vs. 44.7 ± 1.7; mFreq, 4.6 ± 0.8 vs. 5.0 ± 0.9 | Quantal content, 0.079; mFreq, 0.750 |
| Toxin (company) . | Number of mice (number of NMJs) . | Results (before vs. after toxin) . | Nested ANOVA (P value) . |
|---|---|---|---|
| Iberiotoxin (Sigma-Aldrich), 400 nM | 4 (43 before, 51 after) | Quantal content, 58.8 ± 2.6 vs. 60.0 ± 2.4; mFreq, 2.8 ± 0.7 vs. 4.0 ± 0.6 | Quantal content, 0.825; mFreq, 0.224 |
| Iberiotoxin (Cayman), 400 nM | 3 (37 before, 50 after) | Quantal content, 41.5 ± 2.7 vs. 41.7 ± 2.2; mFreq, 3.58 ± 0.6 vs. 4.7 ± 0.5 | Quantal content, 0.959; mFreq, 0.121 |
| Charybdotoxin (Alomone), 400 nM | 6 (70 before, 96 after) | Quantal content, 57.8 ± 1.8 vs. 55.3 ± 1.5; mFreq, 4.8 ± 0.7 vs. 4.8 ± 0.6 | Quantal content, 0.287; mFreq, 0.926 |
| Charybdotoxin (Cayman), 400 nM | 3 (45 before, 56 after) | Quantal content, 57.9 ± 2.7 vs. 56.2 ± 2.4; mFreq, 6.1 ± 0.8 vs. 7.8 ± 0.7 | Quantal content, 0.628; mFreq, 0.119 |
| Paxilline (Sigma-Aldrich), 10 µM | 5 (55 before, 63 after) | Quantal content, 48.6 ± 1.5 vs. 44.7 ± 1.7; mFreq, 4.6 ± 0.8 vs. 5.0 ± 0.9 | Quantal content, 0.079; mFreq, 0.750 |
Results are shown as mean ± SEM. mFreq, frequency of mEPCs in the absence of nerve stimulation.