| . | τ1 (ms) . | Area1 (%) . | τ2 (ms) . | Area2 (%) . | τ3 (ms) . | Area3 (%) . | τ4 (ms) . | Area4 (%) . | τ5 (ms) . | Area5 (%) . | Patches (n) . |
|---|---|---|---|---|---|---|---|---|---|---|---|
| GluN2A WT | 0.037 ± 0.002 | 27 ± 2 | 0.31 ± 0.029 | 20 ± 1 | 1.1 ± 0.18 | 17 ± 12 | 2.3 ± 0.32 | 8 ± 3 | 5.1 ± 0.22 | 28 ± 2 | 6 |
| GluN2A-L550A | 0.088 ± 0.012 | 21 ± 3 | – | – | 0.70 ± 0.21 | 18 ± 2 | 9.5 ± 1.6 | 19 ± 5 | 36 ± 3.7 | 41 ± 5 | 7 |
| GluN2A-E551A | 0.035 ± 0.0002 | 21 ± 2 | 0.33 ± 0.010 | 15 ± 1 | 1.1 ± 0.033 | 31 ± 5 | 3.8 ± 0.31 | 22 ± 8 | 4.2 ± 0.58 | 11 ± 5 | 3 |
| GluN2A-P552A | 0.041 ± 0.004 | 25 ± 4 | 0.36 ± 0.071 | 22 ± 3 | 1.4 ± 0.18 | 24 ± 9 | 4.7 ± 0.33 | 29 ± 4 | – | – | 6 |
| GluN2A-F553A | 0.058 ± 0.018 | 11 ± 1 | – | – | 1.1 ± 0.054 | 16 ± 2 | 7.5 ± 2.6 | 36 ± 5 | 14 ± 1.8 | 37 ± 7 | 3 |
| GluN2A-A555P | 0.049 ± 0.007 | 27 ± 4 | 0.54 ± 0.16 | 25 ± 2 | 1.1 ± 0.26 | 21 ± 8 | 3.8 ± 0.86 | 20 ± 8 | 9.6 ± 3.4 | 11 ± 7 | 3 |
| GluN2A-F553Y | 0.034 ± 0.0003 | 31 ± 4 | 0.30 ± 0.021 | 17 ± 1 | 2.5 ± 0.67 | 13 ± 3 | 5.4 ± 1.2 | 5 ± 1 | 12 ± 4.7 | 16 ± 9 | 3 |
| . | τ1 (ms) . | Area1 (%) . | τ2 (ms) . | Area2 (%) . | τ3 (ms) . | Area3 (%) . | τ4 (ms) . | Area4 (%) . | τ5 (ms) . | Area5 (%) . | Patches (n) . |
|---|---|---|---|---|---|---|---|---|---|---|---|
| GluN2A WT | 0.037 ± 0.002 | 27 ± 2 | 0.31 ± 0.029 | 20 ± 1 | 1.1 ± 0.18 | 17 ± 12 | 2.3 ± 0.32 | 8 ± 3 | 5.1 ± 0.22 | 28 ± 2 | 6 |
| GluN2A-L550A | 0.088 ± 0.012 | 21 ± 3 | – | – | 0.70 ± 0.21 | 18 ± 2 | 9.5 ± 1.6 | 19 ± 5 | 36 ± 3.7 | 41 ± 5 | 7 |
| GluN2A-E551A | 0.035 ± 0.0002 | 21 ± 2 | 0.33 ± 0.010 | 15 ± 1 | 1.1 ± 0.033 | 31 ± 5 | 3.8 ± 0.31 | 22 ± 8 | 4.2 ± 0.58 | 11 ± 5 | 3 |
| GluN2A-P552A | 0.041 ± 0.004 | 25 ± 4 | 0.36 ± 0.071 | 22 ± 3 | 1.4 ± 0.18 | 24 ± 9 | 4.7 ± 0.33 | 29 ± 4 | – | – | 6 |
| GluN2A-F553A | 0.058 ± 0.018 | 11 ± 1 | – | – | 1.1 ± 0.054 | 16 ± 2 | 7.5 ± 2.6 | 36 ± 5 | 14 ± 1.8 | 37 ± 7 | 3 |
| GluN2A-A555P | 0.049 ± 0.007 | 27 ± 4 | 0.54 ± 0.16 | 25 ± 2 | 1.1 ± 0.26 | 21 ± 8 | 3.8 ± 0.86 | 20 ± 8 | 9.6 ± 3.4 | 11 ± 7 | 3 |
| GluN2A-F553Y | 0.034 ± 0.0003 | 31 ± 4 | 0.30 ± 0.021 | 17 ± 1 | 2.5 ± 0.67 | 13 ± 3 | 5.4 ± 1.2 | 5 ± 1 | 12 ± 4.7 | 16 ± 9 | 3 |
Closed time distributions were fitted (maximum likelihood) by four to five exponential components. Fitted parameters are expressed as mean ± SEM to two significant figures.