Table 1.
At 10 mM K+, mean resting EM of unexcitable fibers was less negative for HyperKPP soleus fibers than wild type fibers
[Ca2+]e (mM)[Mg2+]e (mM)Wild type soleusHyperKPP soleus
2.4 3.1 −63.6 ± 1.3 (38/11) −56.1 ± 1.2 (37/6)a 
0.3 3.1 −61.7 ± 2.2 (62/8) −55.1 ± 1.8 (75/6)a 
0.3 5.2 −59.4 ± 1.3 (54/6) −56.4 ± 1.1 (98/6)a 
[Ca2+]e (mM)[Mg2+]e (mM)Wild type soleusHyperKPP soleus
2.4 3.1 −63.6 ± 1.3 (38/11) −56.1 ± 1.2 (37/6)a 
0.3 3.1 −61.7 ± 2.2 (62/8) −55.1 ± 1.8 (75/6)a 
0.3 5.2 −59.4 ± 1.3 (54/6) −56.4 ± 1.1 (98/6)a 

Unexcitable fibers were fibers that did not generate an action potential upon stimulation. Mean resting EM values are expressed as mean ± SE (number of fibers/number of muscle). There was no significant effect of 5 µM salbutamol on mean resting EM of unexcitable fibers at 10 mM K+ (data not shown). ANOVA, P > 0.05.

a

Mean resting EM of unexcitable HyperKPP soleus fibers significantly different from that of wild type. ANOVA and LSD, P < 0.05.

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