| [Ca2+]e (mM) . | [Mg2+]e (mM) . | Wild type soleus . | HyperKPP soleus . |
|---|---|---|---|
| 2.4 | 3.1 | −63.6 ± 1.3 (38/11) | −56.1 ± 1.2 (37/6)a |
| 0.3 | 3.1 | −61.7 ± 2.2 (62/8) | −55.1 ± 1.8 (75/6)a |
| 0.3 | 5.2 | −59.4 ± 1.3 (54/6) | −56.4 ± 1.1 (98/6)a |
| [Ca2+]e (mM) . | [Mg2+]e (mM) . | Wild type soleus . | HyperKPP soleus . |
|---|---|---|---|
| 2.4 | 3.1 | −63.6 ± 1.3 (38/11) | −56.1 ± 1.2 (37/6)a |
| 0.3 | 3.1 | −61.7 ± 2.2 (62/8) | −55.1 ± 1.8 (75/6)a |
| 0.3 | 5.2 | −59.4 ± 1.3 (54/6) | −56.4 ± 1.1 (98/6)a |
Unexcitable fibers were fibers that did not generate an action potential upon stimulation. Mean resting EM values are expressed as mean ± SE (number of fibers/number of muscle). There was no significant effect of 5 µM salbutamol on mean resting EM of unexcitable fibers at 10 mM K+ (data not shown). ANOVA, P > 0.05.
Mean resting EM of unexcitable HyperKPP soleus fibers significantly different from that of wild type. ANOVA and LSD, P < 0.05.