Table 3.
Parameters from Hill fits to [Na+i] dependence, when Na+i is exchanged with NMDG+i or K+i
Na+i with NMDG+iNa+i with K+i
ConditionK0.5 (mM)Imax (pA)HnK0.5 (mM)Imax (pA)Hn
α1β1 3.1 ± 0.9 7.0 ± 2.9 1.2 10 13.8 ± 2.3 10.2 ± 3.9 2.8 18 
FXYD1 2.9 ± 0.6 5.7 ± 1.6 1.4 9 19.5 ± 6.6*** 5.6 ± 1.5 2.2 31 
FXYD2 3.5 ± 0.8 10.3 ± 10.3 1.7 7 18.1 ± 2.4** 5.3 ± 0.4 3.0 6 
FXYD4 2.4 ± 0.6 5.1 ± 1.2 1.2 4 10.4 ± 1.7** 8.5 ± 5.2 2.6 9 
FXYD6 3.4 ± 0.6 6.2 ± 2.5 1.5 10 20.7 ± 3.2** 4.6 ± 0.8 2.8 6 
FXYD7 3.0 ± 0.5 5.5 ± 1.0 1.3 6 10.5 ± 2.6* 6.1 ± 3.0 2.2 7 

Errors represent SD, H = Hill coefficient, and n = number of experiments. Significantly different with respect to α1β1 alone: *, P < 0.01 and **, P < 0.001 (t test); ***, P < 0.05 (Mann–Whitney U test).

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