Table 3. Parameters from Hill fits to... | Rockefeller University Press

Table 3.

Parameters from Hill fits to [Na⁺_i] dependence, when Na⁺_i is exchanged with NMDG⁺_i or K⁺_i

	Na⁺_i with NMDG⁺_i				Na⁺_i with K⁺_i
Condition	K_0.5 (mM)	I_max (pA)	H	n	K_0.5 (mM)	I_max (pA)	H	n
α1β1	3.1 ± 0.9	7.0 ± 2.9	1.2	10	13.8 ± 2.3	10.2 ± 3.9	2.8	18
FXYD1	2.9 ± 0.6	5.7 ± 1.6	1.4	9	19.5 ± 6.6***	5.6 ± 1.5	2.2	31
FXYD2	3.5 ± 0.8	10.3 ± 10.3	1.7	7	18.1 ± 2.4**	5.3 ± 0.4	3.0	6
FXYD4	2.4 ± 0.6	5.1 ± 1.2	1.2	4	10.4 ± 1.7**	8.5 ± 5.2	2.6	9
FXYD6	3.4 ± 0.6	6.2 ± 2.5	1.5	10	20.7 ± 3.2**	4.6 ± 0.8	2.8	6
FXYD7	3.0 ± 0.5	5.5 ± 1.0	1.3	6	10.5 ± 2.6*	6.1 ± 3.0	2.2	7

	Na⁺_i with NMDG⁺_i				Na⁺_i with K⁺_i
Condition	K_0.5 (mM)	I_max (pA)	H	n	K_0.5 (mM)	I_max (pA)	H	n
α1β1	3.1 ± 0.9	7.0 ± 2.9	1.2	10	13.8 ± 2.3	10.2 ± 3.9	2.8	18
FXYD1	2.9 ± 0.6	5.7 ± 1.6	1.4	9	19.5 ± 6.6***	5.6 ± 1.5	2.2	31
FXYD2	3.5 ± 0.8	10.3 ± 10.3	1.7	7	18.1 ± 2.4**	5.3 ± 0.4	3.0	6
FXYD4	2.4 ± 0.6	5.1 ± 1.2	1.2	4	10.4 ± 1.7**	8.5 ± 5.2	2.6	9
FXYD6	3.4 ± 0.6	6.2 ± 2.5	1.5	10	20.7 ± 3.2**	4.6 ± 0.8	2.8	6
FXYD7	3.0 ± 0.5	5.5 ± 1.0	1.3	6	10.5 ± 2.6*	6.1 ± 3.0	2.2	7

Errors represent SD, H = Hill coefficient, and n = number of experiments. Significantly different with respect to α1β1 alone: *, P < 0.01 and **, P < 0.001 (t test); ***, P < 0.05 (Mann–Whitney U test).

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