Table 3.
Unitary parameters estimated from fluctuation analysis
KainateCdCdKainate + Cd
10 µM50 µM500 µM10 + 50 µM
GluK2(Q) L10C     
Unitary current (fA) 92 ± 8 83 ± 13 76 ± 11 79 ± 9 
Unitary conductance (pS) 1.15 ± 0.10 1.04 ± 0.16 0.94 ± 0.14 0.99 ± 0.11 
g Cd/g K  0.93 ± 0.07 0.81 ± 0.05 0.85 ± 0.04 
Maximal current (pA) 212 ± 38 75 ± 4 218 ± 18 412 ± 38 
Open probability 0.21 ± 0.03 0.09 ± 0.02 0.30 ± 0.05 0.48 ± 0.03 
Po Cd/Po 0.4 ± 0.1 1.7 ± 0.5 3.9 ± 1.3 
Number of cells 10 10 
GluK2(R) A8C     
Unitary current (fA) 15.7 ± 3.0 4.4 ± 0.9 4.0 ± 0.7  
Unitary conductance (fS) 197 ± 37 55 ± 11 50 ± 9  
g Cd/g K  0.39 ± 0.07 0.32 ± 0.08  
Maximal current (pA) 473 ± 158 1,350 ± 300 860 ± 130  
Po Cd/Po 27 ± 13 20 ± 6  
Number of cells 16 16  
KainateCdCdKainate + Cd
10 µM50 µM500 µM10 + 50 µM
GluK2(Q) L10C     
Unitary current (fA) 92 ± 8 83 ± 13 76 ± 11 79 ± 9 
Unitary conductance (pS) 1.15 ± 0.10 1.04 ± 0.16 0.94 ± 0.14 0.99 ± 0.11 
g Cd/g K  0.93 ± 0.07 0.81 ± 0.05 0.85 ± 0.04 
Maximal current (pA) 212 ± 38 75 ± 4 218 ± 18 412 ± 38 
Open probability 0.21 ± 0.03 0.09 ± 0.02 0.30 ± 0.05 0.48 ± 0.03 
Po Cd/Po 0.4 ± 0.1 1.7 ± 0.5 3.9 ± 1.3 
Number of cells 10 10 
GluK2(R) A8C     
Unitary current (fA) 15.7 ± 3.0 4.4 ± 0.9 4.0 ± 0.7  
Unitary conductance (fS) 197 ± 37 55 ± 11 50 ± 9  
g Cd/g K  0.39 ± 0.07 0.32 ± 0.08  
Maximal current (pA) 473 ± 158 1,350 ± 300 860 ± 130  
Po Cd/Po 27 ± 13 20 ± 6  
Number of cells 16 16  

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