Table 2. Time constants for Cd... | Rockefeller University Press

Table 2.

Time constants for Cd activation and inhibition

Construct	Activation (s)		Cells (no.)	[Cd]	Inhibition (s)		Cells (no.)	[Cd]
Construct	Tau on	Tau off	Cells (no.)	[Cd]	Tau on	Tau off	Cells (no.)	[Cd]
GluK2 WT (KA-evoked)					0.51 ± 0.10	2.49 ± 0.48	8	5 mM
GluK2 A8C	0.81 ± 0.06	8.41 ± 1.07	94	50 µM
	0.10 ± 0.01	9.91 ± 3.10	19	20 mM	0.33 ± 0.04	0.60 ± 0.07	19	20 mM
K2(Q) L10C	0.71 ± 0.15	1.52 ± 0.25	16	1 mM
N1/K2 A8C + N2B/K2 A8C	0.90 ± 0.23	5.95 ± 0.91	35	50 µM
	0.10 ± 0.01	8.68 ± 2.73	11	5 mM	0.39 ± 0.05	1.12 ± 0.13	11	5 mM
N1/K2 A8C + N2B/K2	0.88 ± 0.13	2.91 ± 0.63	30	50 µM
	0.11 ± 0.02	1.87 ± 0.12	13	5 mM	0.37 ± 0.05	0.67 ± 0.06	13	5 mM
N1/K2 + N2B/K2 A8C	0.97 ± 0.17	3.24 ± 0.60	33	50 µM
	0.09 ± 0.02	3.91 ± 0.87	10	5 mM	0.22 ± 0.02	0.66 ± 0.06	10	5 mM

Construct	Activation (s)		Cells (no.)	[Cd]	Inhibition (s)		Cells (no.)	[Cd]
Construct	Tau on	Tau off	Cells (no.)	[Cd]	Tau on	Tau off	Cells (no.)	[Cd]
GluK2 WT (KA-evoked)					0.51 ± 0.10	2.49 ± 0.48	8	5 mM
GluK2 A8C	0.81 ± 0.06	8.41 ± 1.07	94	50 µM
	0.10 ± 0.01	9.91 ± 3.10	19	20 mM	0.33 ± 0.04	0.60 ± 0.07	19	20 mM
K2(Q) L10C	0.71 ± 0.15	1.52 ± 0.25	16	1 mM
N1/K2 A8C + N2B/K2 A8C	0.90 ± 0.23	5.95 ± 0.91	35	50 µM
	0.10 ± 0.01	8.68 ± 2.73	11	5 mM	0.39 ± 0.05	1.12 ± 0.13	11	5 mM
N1/K2 A8C + N2B/K2	0.88 ± 0.13	2.91 ± 0.63	30	50 µM
	0.11 ± 0.02	1.87 ± 0.12	13	5 mM	0.37 ± 0.05	0.67 ± 0.06	13	5 mM
N1/K2 + N2B/K2 A8C	0.97 ± 0.17	3.24 ± 0.60	33	50 µM
	0.09 ± 0.02	3.91 ± 0.87	10	5 mM	0.22 ± 0.02	0.66 ± 0.06	10	5 mM