| Ion channel . | Cluster area (nm2) . | Cluster density (clusters/µm2) . | Steady-state Pg, PR, Pn . | |||
|---|---|---|---|---|---|---|
| Short dwell time . | Long dwell time . | Short dwell time . | Long dwell time . | Short dwell time . | Long dwell time . | |
| Smooth muscle | ||||||
| CaV1.2 | 2,481 | 2,479 | 9.7 | 9.7 | Pg = 0.1 | Pg = 0.01 |
| PR = 0.0012803 | PR = 0.0001609 | |||||
| Pn = 0.000043648 | Pn = 0.00000519639 | |||||
| TRPV4 | 1,819 | 1,851 | 7.8 | 7.8 | Pg = 0.1 | Pg = 0.01 |
| PR = 0.0020398 | PR = 0.00027071 | |||||
| Pn = 0.000039526 | Pn =0.000004824 | |||||
| BK | 2,981 | 3,030 | 9.2 | 9.24 | Pg = 0.1 | Pg = 0.01 |
| PR = 0.00097263 | PR = 0.000119 | |||||
| Pn = 0.000036651 | Pn = 0.000004355 | |||||
| Cardiac muscle | ||||||
| CaV1.2 | 2,559 | 2,543 | 21.9 | 21.8 | Pg = 0.1 | Pg = 0.01 |
| PR = 0.0010796 | PR = 0.00013367 | |||||
| Pn = 0.00011952 | Pn = 0.000014258 | |||||
| Hippocampal neurons | ||||||
| CaV1.3 | 3,657 | 3,697 | 23.2 | 23.4 | Pg = 0.1 | Pg = 0.01 |
| PR = 0.00052117 | PR = 0.00006295399 | |||||
| Pn = 0.0001249 | Pn = 0.000014666 | |||||
| tsA-201 cells | ||||||
| CaV1.3S | 2,103 | 2,127 | 17.1 | 15.8 | Pg = 0.05 | Pg = 0.005 |
| PR = 0.00086217 | PR = 0.00010066 | |||||
| Pn = 0.000044351 | Pn = 0.00000476312 | |||||
| CaV1.3L | 2,539 | 2,558 | 14.8 | 15.0 | Pg = 0.05 | Pg = 0.005 |
| PR = 0.00058827 | PR = 0.0000787855 | |||||
| Pn = 0.000036252 | Pn = 0.0000042249 | |||||
| Ion channel . | Cluster area (nm2) . | Cluster density (clusters/µm2) . | Steady-state Pg, PR, Pn . | |||
|---|---|---|---|---|---|---|
| Short dwell time . | Long dwell time . | Short dwell time . | Long dwell time . | Short dwell time . | Long dwell time . | |
| Smooth muscle | ||||||
| CaV1.2 | 2,481 | 2,479 | 9.7 | 9.7 | Pg = 0.1 | Pg = 0.01 |
| PR = 0.0012803 | PR = 0.0001609 | |||||
| Pn = 0.000043648 | Pn = 0.00000519639 | |||||
| TRPV4 | 1,819 | 1,851 | 7.8 | 7.8 | Pg = 0.1 | Pg = 0.01 |
| PR = 0.0020398 | PR = 0.00027071 | |||||
| Pn = 0.000039526 | Pn =0.000004824 | |||||
| BK | 2,981 | 3,030 | 9.2 | 9.24 | Pg = 0.1 | Pg = 0.01 |
| PR = 0.00097263 | PR = 0.000119 | |||||
| Pn = 0.000036651 | Pn = 0.000004355 | |||||
| Cardiac muscle | ||||||
| CaV1.2 | 2,559 | 2,543 | 21.9 | 21.8 | Pg = 0.1 | Pg = 0.01 |
| PR = 0.0010796 | PR = 0.00013367 | |||||
| Pn = 0.00011952 | Pn = 0.000014258 | |||||
| Hippocampal neurons | ||||||
| CaV1.3 | 3,657 | 3,697 | 23.2 | 23.4 | Pg = 0.1 | Pg = 0.01 |
| PR = 0.00052117 | PR = 0.00006295399 | |||||
| Pn = 0.0001249 | Pn = 0.000014666 | |||||
| tsA-201 cells | ||||||
| CaV1.3S | 2,103 | 2,127 | 17.1 | 15.8 | Pg = 0.05 | Pg = 0.005 |
| PR = 0.00086217 | PR = 0.00010066 | |||||
| Pn = 0.000044351 | Pn = 0.00000476312 | |||||
| CaV1.3L | 2,539 | 2,558 | 14.8 | 15.0 | Pg = 0.05 | Pg = 0.005 |
| PR = 0.00058827 | PR = 0.0000787855 | |||||
| Pn = 0.000036252 | Pn = 0.0000042249 | |||||