| Variable/parameter . | Units . | Definition/meaning . |
|---|---|---|
| µM | Calcium in the cytoplasm | |
| µM | Calcium in the ER (SpApp) | |
| D | Diffusion rate | |
| Bm | µM | Mobile buffers |
| Bf | Mol/(µm2 s) | Fixed buffers |
| PDE | Partial differential equation | |
| ODE | Ordinary differential equation | |
| Jx | Mol/(µm2 s) | Boundary flux due to x |
| CBP | µM | Calcium-binding proteins (calcium buffers) |
| Vcyto | µm3 | Volume of the cytoplasm excluding the SpApp volume |
| PM | Plasma membrane | |
| SpApp | Spine apparatus | |
| ECS | Extracellular space | |
| n | µm | Scale factor to convert between volume reactions to boundary flux |
| nPM | µm | Volume-to-surface area ratio of the cytoplasm to the PM |
| nSpApp | µm | Volume-to-surface area ratio of the SpApp volume to the SpApp surface area |
| AUC | Ions/s | Area under the curve |
| EPSP | mV | Excitatory postsynaptic potential |
| BPAP | mV | Back-propagating action potential |
| NMDAR | N-methyl-D-aspartate receptor | |
| VSCC | Voltage-sensitive calcium channel | |
| PMCA | Plasma membrane calcium ATPase | |
| NCX | Sodium–calcium exchanger |
| Variable/parameter . | Units . | Definition/meaning . |
|---|---|---|
| µM | Calcium in the cytoplasm | |
| µM | Calcium in the ER (SpApp) | |
| D | Diffusion rate | |
| Bm | µM | Mobile buffers |
| Bf | Mol/(µm2 s) | Fixed buffers |
| PDE | Partial differential equation | |
| ODE | Ordinary differential equation | |
| Jx | Mol/(µm2 s) | Boundary flux due to x |
| CBP | µM | Calcium-binding proteins (calcium buffers) |
| Vcyto | µm3 | Volume of the cytoplasm excluding the SpApp volume |
| PM | Plasma membrane | |
| SpApp | Spine apparatus | |
| ECS | Extracellular space | |
| n | µm | Scale factor to convert between volume reactions to boundary flux |
| nPM | µm | Volume-to-surface area ratio of the cytoplasm to the PM |
| nSpApp | µm | Volume-to-surface area ratio of the SpApp volume to the SpApp surface area |
| AUC | Ions/s | Area under the curve |
| EPSP | mV | Excitatory postsynaptic potential |
| BPAP | mV | Back-propagating action potential |
| NMDAR | N-methyl-D-aspartate receptor | |
| VSCC | Voltage-sensitive calcium channel | |
| PMCA | Plasma membrane calcium ATPase | |
| NCX | Sodium–calcium exchanger |