Table 1. VIP and CCh modulate CFTR... | Rockefeller University Press

Table 1.

VIP and CCh modulate CFTR distribution and confined mobility at the cell surface of pHBE cells through lipid-dependent mechanisms

Treatment	CD ratio	DA ratio	D_micro (µm²/s) × 0.001	f_micro	R (μm)	n_cell^{^a}	N_exp^{^b}
Ctr	1.0 ± 0.1	1.0 ± 0.1	10.9 ± 0.6	0.21 ± 0.02	0.322 ± 0.005	224	10
VIP	0.50 ± 0.05^{^c}	2.7 ± 0.4^{^d}	3.3 ± 0.2^{^c}	0.40 ± 0.03^{^d}	0.279 ± 0.005^{^c}	164	8
CCh	0.38 ± 0.08^{^c}	2.5 ± 0.3^{^d}	4.77 ± 0.6^{^c}	0.35 ± 0.04^{^d}	0.283 ± 0.004^{^c}	40	2
COase +VIP	0.87 ± 0.08	1.0 ± 0.1	10.7 ± 0.7	0.18 ± 0.02	0.303 ± 0.005	112	4
Ami +VIP	1.4 ± 0.2^{^d}	0.50 ± 0.07^{^c}	18.0 ± 1.0^{^d}	0.14 ± 0.01^{^c}	0.335 ± 0.005	85	4

Treatment	CD ratio	DA ratio	D_micro (µm²/s) × 0.001	f_micro	R (μm)	n_cell^a	N_exp^b
Ctr	1.0 ± 0.1	1.0 ± 0.1	10.9 ± 0.6	0.21 ± 0.02	0.322 ± 0.005	224	10
VIP	0.50 ± 0.05^c	2.7 ± 0.4^d	3.3 ± 0.2^c	0.40 ± 0.03^d	0.279 ± 0.005^c	164	8
CCh	0.38 ± 0.08^c	2.5 ± 0.3^d	4.77 ± 0.6^c	0.35 ± 0.04^d	0.283 ± 0.004^c	40	2
COase +VIP	0.87 ± 0.08	1.0 ± 0.1	10.7 ± 0.7	0.18 ± 0.02	0.303 ± 0.005	112	4
Ami +VIP	1.4 ± 0.2^d	0.50 ± 0.07^c	18.0 ± 1.0^d	0.14 ± 0.01^c	0.335 ± 0.005	85	4

(n_cell) total number of cells

(N_exp) number of independent experiments

Smaller than Ctr, p_cell < 0.001, p_exp < 0.05.

Larger than Ctr, p_cell < 0.001, p_exp < 0.05

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