Table 1. Activation and deactivation G-V... | Rockefeller University Press

Table 1.

Activation and deactivation G-V Boltzmann fit parameters recorded with physiological durations

	Activation G-V V_1/2 (mV)	k	Deactivation G-V V_1/2 (mV)	k	Mode shift V_1/2 (mV)
WT
pH 7.4	−12.4 ± 1.1 (6)	9.9 ± 0.4	−66.0 ± 0.9 (6)	7.3 ± 0.2	−53.6 ± 1.8
pH 6.5	−5.9 ± 0.7 (6)	11.2 ± 0.3	−43.0 ± 0.7 (6)	6.4 ± 0.1	−37.1 ± 1.1
D509A
pH 7.4	+17.1 ± 0.8 (5)	14.7 ± 0.4	+1.6 ± 1.1 (5)	12.0 ± 0.4	−15.5 ± 1.4
pH 6.5	+21.6 ± 1.5 (5)	15.1 ± 0.2	+4.8 ± 1.2 (5)	11.6 ± 0.3	−16.8 ± 1.9

	Activation G-V V_1/2 (mV)	k	Deactivation G-V V_1/2 (mV)	k	Mode shift V_1/2 (mV)
WT
pH 7.4	−12.4 ± 1.1 (6)	9.9 ± 0.4	−66.0 ± 0.9 (6)	7.3 ± 0.2	−53.6 ± 1.8
pH 6.5	−5.9 ± 0.7 (6)	11.2 ± 0.3	−43.0 ± 0.7 (6)	6.4 ± 0.1	−37.1 ± 1.1
D509A
pH 7.4	+17.1 ± 0.8 (5)	14.7 ± 0.4	+1.6 ± 1.1 (5)	12.0 ± 0.4	−15.5 ± 1.4
pH 6.5	+21.6 ± 1.5 (5)	15.1 ± 0.2	+4.8 ± 1.2 (5)	11.6 ± 0.3	−16.8 ± 1.9

Data are expressed as mean ± SEM, with the number of cells in parentheses.