| Hemichannel | V 1/2 | z | ΔG(V1/2) |
|---|---|---|---|
| WT | 9.659 | 2.444 | −0.934 |
| N14K | −6.738 | 0.967 | 0.258 |
| H100A | 9.082 | 1.471 | −0.529 |
| N14K/H100A | −1.629 | 1.156 | 0.074 |
| E101A | 7.674 | 1.881 | −0.571 |
| N14K/E101A | −42.203 | 1.143 | 1.911 |
| Hemichannel | Δ | ||
|---|---|---|---|
| WT | 9.659 | 2.444 | −0.934 |
| N14K | −6.738 | 0.967 | 0.258 |
| H100A | 9.082 | 1.471 | −0.529 |
| N14K/H100A | −1.629 | 1.156 | 0.074 |
| E101A | 7.674 | 1.881 | −0.571 |
| N14K/E101A | −42.203 | 1.143 | 1.911 |
Summary of the V1/2, z, and ΔG values for the hCx26 WT and each one of the single and double mutant channels.
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