| . | K280N (N = 1, n = 16) . | Donors (N = 2, n = 12) . | LVHao (N = 3, n = 13) . | HCMsmn (N = 6, n = 29) . |
|---|---|---|---|---|
| Maximal tension (kN m−2) | 13.5 ± 1.8* | 38.7 ± 1.2 | 21.3 ± 1.5 | 25.6 ± 1.6 |
| Maximal ATPase activity (μmol L−1 s−1) | 38.4 ± 4.8 | 91.0 ± 4.7 | 52.2 ± 6.3 | 45.2 ± 2.7 |
| Tension cost (μmol L−1 s−1/ kN m−2) | 3.1 ± 0.3* | 2.3 ± 0.1 | 2.5 ± 0.3 | 1.8 ± 0.1 |
| Basal ATPase activity (μmol L−1 s−1) | 4.6 ± 0.8 | 10.9 ± 2.1 | 10.3 ± 2.2 | 7.2 ± 1.0 |
| . | K280N (N = 1, n = 16) . | Donors (N = 2, n = 12) . | LVHao (N = 3, n = 13) . | HCMsmn (N = 6, n = 29) . |
|---|---|---|---|---|
| Maximal tension (kN m−2) | 13.5 ± 1.8* | 38.7 ± 1.2 | 21.3 ± 1.5 | 25.6 ± 1.6 |
| Maximal ATPase activity (μmol L−1 s−1) | 38.4 ± 4.8 | 91.0 ± 4.7 | 52.2 ± 6.3 | 45.2 ± 2.7 |
| Tension cost (μmol L−1 s−1/ kN m−2) | 3.1 ± 0.3* | 2.3 ± 0.1 | 2.5 ± 0.3 | 1.8 ± 0.1 |
| Basal ATPase activity (μmol L−1 s−1) | 4.6 ± 0.8 | 10.9 ± 2.1 | 10.3 ± 2.2 | 7.2 ± 1.0 |
Means ± SE; N, number of patients in the group; n, number of muscle strips. For the statistics of the comparison between groups, see Supplemental materials; *, K280N parameters for which the statistical analysis shows a significant difference versus control groups.