Table 1. Summary of steady-state... | Rockefeller University Press

Table 1.

Summary of steady-state mechanical measurements

Measurement	WT_SV129 (9)	FT-WT₀ (8)	cMyBP-C null (8)
P_Tot (mN/mm²)	39.8 ± 3.6	30.1 ± 5.2	21.7 ± 3.1
P_o (mN/mm²)	38.1 ± 3.6	27.9 ± 5.2	19.8 ± 3.0
P_rest (mN/mm²)	1.7 ± 0.2	2.2 ± 0.3	1.9 ± 0.2
%P_rest	4.3 ± 0.1	8.6 ± 1.6	9.7 ± 1.9
n_H	3.4 ± 0.1	3.4 ± 0.1	3.2 ± 0.2
pCa₅₀	5.82 ± 0.02	5.78 ± 0.02	5.77 ± 0.02
ktr (s⁻¹)	25.9 ± 2.0	29.3 ± 1.2	38.2 ± 1.7^{^a}

Measurement	WT_SV129 (9)	FT-WT₀ (8)	cMyBP-C null (8)
P_Tot (mN/mm²)	39.8 ± 3.6	30.1 ± 5.2	21.7 ± 3.1
P_o (mN/mm²)	38.1 ± 3.6	27.9 ± 5.2	19.8 ± 3.0
P_rest (mN/mm²)	1.7 ± 0.2	2.2 ± 0.3	1.9 ± 0.2
%P_rest	4.3 ± 0.1	8.6 ± 1.6	9.7 ± 1.9
n_H	3.4 ± 0.1	3.4 ± 0.1	3.2 ± 0.2
pCa₅₀	5.82 ± 0.02	5.78 ± 0.02	5.77 ± 0.02
ktr (s⁻¹)	25.9 ± 2.0	29.3 ± 1.2	38.2 ± 1.7^{^a}

All values are expressed as means ± SEM, with the number of trabecular preparations listed in parentheses. ktr, maximal rate of tension redevelopment at pCa 4.5; n_H, Hill coefficient for Ca²⁺-activated tension–pCa relationship; pCa₅₀, pCa required for half-maximal activation; P_rest, Ca²⁺-independent tension at pCa 9.0; P_o, maximal Ca²⁺-activated tension at pCa 4.5; P_Tot, maximal Ca²⁺-activated tension (maximal Ca²⁺-activated tension plus Ca²⁺-independent tension).

Significantly different from WT and FT-WT mice (P < 0.05).

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