Table 1.
Mouse cone flash response parameters
Genotypenrmax (pA)I1/2 (P*)Time to peak (ms)τrec (ms)A (s−2)Rin (MΩ)Cm (pF)
C57BL/6J cones 13 30 ± 2.0 470 ± 89 41 ± 1.9 200 ± 18 5.3 ± 0.4 850 ± 120 7.5 ± 0.5 
    24 ± 0.6 155 ± 28    
C57BL/6J rods 17 ± 1.6 14 ± 2.4 200 ± 17 130 ± 23 4.6 ± 0.3 4,000 ± 680 3.6 ± 0.3 
    140 ± 20 260 ± 59    
Gnat1−/− cones 25 21 ± 0.9 940 ± 110 59 ± 3.2 28 ± 1.9 2.1 ± 0.2 1,500 ± 350 6.9 ± 0.6 
    33 ± 1.9 42 ± 1.9    
Cx36−/− cones 30 26 ± 1.3 990 ± 93 79 ± 4.8 64 ± 8.5 1.1 ± 0.1 850 ± 130 7.5 ± 0.3 
    50 ± 1.9 61 ± 3.4    
Gnat1−/−;Rv−/− cones 36 20 ± 0.9 1,100 ± 110 55 ± 4.6 33 ± 3.1 1.7 ± 0.1 770 ± 140 6.2 ± 0.3 
    30 ± 2.4 47 ± 2.2    
Gnat1−/−;Gcaps−/− cones 30 14 ± 0.9 740 ± 120 79 ± 5.5 125 ± 28 1.8 ± 0.1 1,200 ± 310 6.6 ± 0.4 
    43 ± 2.4 98 ± 6.4    
Gnat1−/−;Rv−/; Gcaps−/−cones 34 23 ± 1.4 550 ± 51 67 ± 2.4 94 ± 8.5 2.2 ± 0.1 660 ± 27 6.8 ± 0.2 
    42 ± 2.3 110 ± 7.3    
Genotypenrmax (pA)I1/2 (P*)Time to peak (ms)τrec (ms)A (s−2)Rin (MΩ)Cm (pF)
C57BL/6J cones 13 30 ± 2.0 470 ± 89 41 ± 1.9 200 ± 18 5.3 ± 0.4 850 ± 120 7.5 ± 0.5 
    24 ± 0.6 155 ± 28    
C57BL/6J rods 17 ± 1.6 14 ± 2.4 200 ± 17 130 ± 23 4.6 ± 0.3 4,000 ± 680 3.6 ± 0.3 
    140 ± 20 260 ± 59    
Gnat1−/− cones 25 21 ± 0.9 940 ± 110 59 ± 3.2 28 ± 1.9 2.1 ± 0.2 1,500 ± 350 6.9 ± 0.6 
    33 ± 1.9 42 ± 1.9    
Cx36−/− cones 30 26 ± 1.3 990 ± 93 79 ± 4.8 64 ± 8.5 1.1 ± 0.1 850 ± 130 7.5 ± 0.3 
    50 ± 1.9 61 ± 3.4    
Gnat1−/−;Rv−/− cones 36 20 ± 0.9 1,100 ± 110 55 ± 4.6 33 ± 3.1 1.7 ± 0.1 770 ± 140 6.2 ± 0.3 
    30 ± 2.4 47 ± 2.2    
Gnat1−/−;Gcaps−/− cones 30 14 ± 0.9 740 ± 120 79 ± 5.5 125 ± 28 1.8 ± 0.1 1,200 ± 310 6.6 ± 0.4 
    43 ± 2.4 98 ± 6.4    
Gnat1−/−;Rv−/; Gcaps−/−cones 34 23 ± 1.4 550 ± 51 67 ± 2.4 94 ± 8.5 2.2 ± 0.1 660 ± 27 6.8 ± 0.2 
    42 ± 2.3 110 ± 7.3    

For parameters that are dependent on light intensity, two values are reported corresponding to ∼25% (top) and 90% (bottom) of rmax. Values are means ± SEM. Statistical comparisons are given in the text.

or Create an Account

Close Modal
Close Modal