Table 4.
Figure 5 electrophysiological measurements segregated by sex
MeasureWTFGF14−/−Double KO
M (n = 5)F (n = 2)M (n = 0)F (n = 6)M (n = 0)F (n = 9)
Itransdecay τslow (ms) control 13.7 ± 1.5 16.4 ± 3.1  10.5 ± 0.41  11.3 ± 0.42 
Itransdecay τslow (ms) ATX 22 ± 0.6 24.1 ± 1.7  18.1 ± 1.1  17.7 ± 0.44 
V at 50% (mV) control −55 ± 1.1 −54.1 ± 3.3  −57.9 ± 1  −58.5 ± 1.3 
V at 50% (mV) ATX −57.7 ± 1.1 −56.1 ± 4.3  −58.6 ± 1.2  −59.7 ± 1.2 
Relative Iss (%) control 0.8 ± 0.13 0.35 ± 0.1  0.42 ± 0.1  0.62 ± 0.17 
Relative Iss (%) ATX 25.9 ± 1.4 27.9 ± 4.4  11.2 ± 1.5  11.8 ± 1 
Relative Irsg (%) control 4.9 ± 0.48 5.03 ± 0.23  2.79 ± 0.31  3.78 ± 0.42 
Relative Irsg (%) ATX 49.6 ± 1.2 59.2 ± 4.7  30.9 ± 2.6  33.9 ± 1 
IrsgIss (%) control 4.11 ± 0.37 4.68 ± 0.14  2.37 ± 0.27  3.16 ± 0.3 
IrsgIss (%) ATX 23.8 ± 0.89 27 ± 0.3  19.7 ± 1.3  22.1 ± 0.38 
MeasureWTFGF14−/−Double KO
M (n = 5)F (n = 2)M (n = 0)F (n = 6)M (n = 0)F (n = 9)
Itransdecay τslow (ms) control 13.7 ± 1.5 16.4 ± 3.1  10.5 ± 0.41  11.3 ± 0.42 
Itransdecay τslow (ms) ATX 22 ± 0.6 24.1 ± 1.7  18.1 ± 1.1  17.7 ± 0.44 
V at 50% (mV) control −55 ± 1.1 −54.1 ± 3.3  −57.9 ± 1  −58.5 ± 1.3 
V at 50% (mV) ATX −57.7 ± 1.1 −56.1 ± 4.3  −58.6 ± 1.2  −59.7 ± 1.2 
Relative Iss (%) control 0.8 ± 0.13 0.35 ± 0.1  0.42 ± 0.1  0.62 ± 0.17 
Relative Iss (%) ATX 25.9 ± 1.4 27.9 ± 4.4  11.2 ± 1.5  11.8 ± 1 
Relative Irsg (%) control 4.9 ± 0.48 5.03 ± 0.23  2.79 ± 0.31  3.78 ± 0.42 
Relative Irsg (%) ATX 49.6 ± 1.2 59.2 ± 4.7  30.9 ± 2.6  33.9 ± 1 
IrsgIss (%) control 4.11 ± 0.37 4.68 ± 0.14  2.37 ± 0.27  3.16 ± 0.3 
IrsgIss (%) ATX 23.8 ± 0.89 27 ± 0.3  19.7 ± 1.3  22.1 ± 0.38 

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