Table 2.
Summary of biophysical properties of Shaker KV channel mutants
ConstructV½ (mV)s (mV)n
WT ‒23.3 ± 1.1 6.6 ± 0.2 15 
M356R/A359R/R362R (=3R) +24.2 ± 0.9 9.3 ± 0.5 
Y323C ‒5.7 ± 1.8 9.6 ± 1.1 
F324C ‒9.5 ± 1.4 13.4 ± 0.6 10 
T326C ‒10.0 ± 2.4 13.1 ± 0.9 
Y323C/F324C/T326C +17.9 ± 2.5 13.1 ± 0.4 
R365C +19.2 ± 1.0 8.9 ± 0.6 
ConstructV½ (mV)s (mV)n
WT ‒23.3 ± 1.1 6.6 ± 0.2 15 
M356R/A359R/R362R (=3R) +24.2 ± 0.9 9.3 ± 0.5 
Y323C ‒5.7 ± 1.8 9.6 ± 1.1 
F324C ‒9.5 ± 1.4 13.4 ± 0.6 10 
T326C ‒10.0 ± 2.4 13.1 ± 0.9 
Y323C/F324C/T326C +17.9 ± 2.5 13.1 ± 0.4 
R365C +19.2 ± 1.0 8.9 ± 0.6 

V½ and s were determined using Eq. 2 in Materials and methods raised to the power of 1. Data shown as mean ± SEM.

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