Table 3.
Parameters for voltage-dependent activation from tail I–V data for Cav1.4ex47 + CaM12 and Cav1.4ex47-3A
Cav1.4ex47 + CaM12Cav1.4ex47-3AP value
Vh1 (mV) −11 ± 2.2 −7 ± 2.0 0.129a 
Vh2 (mV) 0.02 ± 0.01 0.02 ± 0.02 0.942b 
k1 −7 ± 1.0 −8 ± 1.3 0.762a 
k2 −24 ± 7.2 −22 ± 5.0 0.767a 

Vh and k values (mean ± SEM) were determined from double-Boltzmann fits of the tail I–V data as indicated in the “Methods” section.

a

Student’s t test.

b

Mann–Whitney test.

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