Table 5.
Equilibrium spermine block using the two-conductance model
ReceptorKd(0mV) (µM)h (mV)k (mV)n
MeanSEMMeanSEMMeanSEM
GluA2 1.8 0.2  −14.1 1.7  14.5 1.0 12 
GluA2-γ2 17.9 1.5  −13.4 1.0  15.7 0.5 19 
GluA2 + CNIH-3 5.1 0.8  −11.7 1.1  16.3 0.7 12 
ReceptorKd(0mV) (µM)h (mV)k (mV)n
MeanSEMMeanSEMMeanSEM
GluA2 1.8 0.2  −14.1 1.7  14.5 1.0 12 
GluA2-γ2 17.9 1.5  −13.4 1.0  15.7 0.5 19 
GluA2 + CNIH-3 5.1 0.8  −11.7 1.1  16.3 0.7 12 

Values were obtained by fitting the equilibrium GV relationships; h and k were calculated using the mean b value in Table 4.

or Create an Account

Close Modal
Close Modal