Table 2.
Fit parameters for COSB model (n = 7)
Particle or interactionParametersValues (mean ± SEM)
Pore (L) ΔqL (eo) 0.18 ± 0.01 
 VL (mV) −50 ± 7 
Binding site (K1) Δq1 (eo) 3.4 ± 0.4 
 V1 (mV) 3 ± 1 
Binding site (K2) Δq2 (eo) 1.10 ± 0.08 
 V2 (mV) 12 ± 4 
Blocker concentration [B] (nM) 1.0 [fixed] 
Fractional conductance ϕ 0.2 [fixed] 
Gmin error factor b 0.007 ± 0.002 
Particle or interactionParametersValues (mean ± SEM)
Pore (L) ΔqL (eo) 0.18 ± 0.01 
 VL (mV) −50 ± 7 
Binding site (K1) Δq1 (eo) 3.4 ± 0.4 
 V1 (mV) 3 ± 1 
Binding site (K2) Δq2 (eo) 1.10 ± 0.08 
 V2 (mV) 12 ± 4 
Blocker concentration [B] (nM) 1.0 [fixed] 
Fractional conductance ϕ 0.2 [fixed] 
Gmin error factor b 0.007 ± 0.002 
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